Abstract：
Reproductive problems in cattle are frequent and have an important impact on production. In addition, inflammatory, traumatic and other diseases may be followed by the development of tumours, which are a cause of culling of breeding males. The main types of tumours diagnosed in the bull penis are fibropapilloma and squamous cell carcinoma. The aim of this study was to characterize a case of a tumour in the glans penis of a bull from a dairy farm in Santa Fe, Argentina. The neoplastic tissue was stained with haematoxylin and eosin and then analysed by immunohistochemistry to reveal its characteristic phenotype. Results showed positivity to vimentin, neuron specific enolase, proliferating cell nuclear antigen, S100 and glial fibrillary acidic protein. This suggested that the tumour was a neoplasm of neural origin, classified as neurofibrosarcoma, a peripheral nerve sheath tumour, here reported in the penis of a bull for the first time.
摘要：
牛的生殖问题频繁发生，对生产有重要影响。此外,炎症，创伤和其他疾病可能伴随着肿瘤的发展，这是剔除繁殖雄性的原因。在牛阴茎中诊断出的主要肿瘤类型是纤维乳头状瘤和鳞状细胞癌。这项研究的目的是表征来自圣达菲一家奶牛场的公牛的龟头阴茎肿瘤的病例，阿根廷。肿瘤组织用苏木精和伊红染色，然后通过免疫组织化学分析以揭示其特征表型。结果显示对波形蛋白呈阳性，神经元特异性烯醇化酶，增殖细胞核抗原，S100和胶质纤维酸性蛋白。这表明肿瘤是神经起源的肿瘤，分类为神经纤维肉瘤，周围神经鞘瘤,这里首次报道了公牛的阴茎。
