%0 Journal Article
%T First report of a neurofibrosarcoma in the penis of a bull.
%A Chiaraviglio JA
%A Marini MDR
%A Belotti EM
%A Salvetti NR
%A Ortega HH
%A Mazzini RA
%A Barberis FO
%A Bandeo JY
%A Canal AM
%J J Comp Pathol
%V 213
%N 0
%D 2024 Aug 6
%M 39111235
%F 1.083
%R 10.1016/j.jcpa.2024.07.003
%X Reproductive problems in cattle are frequent and have an important impact on production. In addition, inflammatory, traumatic and other diseases may be followed by the development of tumours, which are a cause of culling of breeding males. The main types of tumours diagnosed in the bull penis are fibropapilloma and squamous cell carcinoma. The aim of this study was to characterize a case of a tumour in the glans penis of a bull from a dairy farm in Santa Fe, Argentina. The neoplastic tissue was stained with haematoxylin and eosin and then analysed by immunohistochemistry to reveal its characteristic phenotype. Results showed positivity to vimentin, neuron specific enolase, proliferating cell nuclear antigen, S100 and glial fibrillary acidic protein. This suggested that the tumour was a neoplasm of neural origin, classified as neurofibrosarcoma, a peripheral nerve sheath tumour, here reported in the penis of a bull for the first time.