Abstract：
There has been an expansion in our understanding of the multifaceted roles of circulating blood cells in regulating haemostasis and contributing to thrombosis. Notably, there is greater recognition of the interplay between coagulation with inflammation and innate immune activation and the contribution of leucocytes. The full blood count (FBC) is a time-honoured test in medicine; however, its components are often viewed in isolation and without consideration of their haemostatic and thrombotic potential. Here, we review how the individual components of the FBC, that is, haemoglobin, platelets and leucocytes, engage with the haemostatic system and focus on both their quantitative and qualitative attributes. We also explore how this information can be harnessed into better management of people with multiple long-term conditions because of their higher risk of adverse clinical events.
摘要：
我们对循环血细胞在调节止血和促进血栓形成中的多方面作用的理解有了扩展。值得注意的是,人们对凝血与炎症和先天免疫激活之间的相互作用以及白细胞的贡献有了更多的认识。全血细胞计数（FBC）是医学上一项历史悠久的测试；但是，它的成分通常是孤立的，不考虑其止血和血栓形成的潜力。这里,我们回顾一下FBC的各个组成部分，也就是说,血红蛋白，血小板和白细胞，参与止血系统，专注于它们的定量和定性属性。我们还探讨了如何利用这些信息来更好地管理患有多种长期疾病的人，因为他们的不良临床事件风险更高。
