METHODS: We included patients with primary open angle glaucoma with at least 12 months of follow-up. We collected and analyzed data on the preoperative characteristics and postoperative outcomes. The primary outcomes were a reduction of ≥20% of the baseline value (criterion A) and/or intraocular pressure between 6 and 21 mmHg (criterion B).
RESULTS: We included 128 eyes with primary open-angle glaucoma. The preoperative mean intraocular pressure was 25.53 ± 6.40 and 35.02 ± 12.57 mmHg in the micropulse- and \"slow cook\" transscleral cyclophotocoagulation groups, respectively (p<0.001). The mean intraocular pressure was reduced significantly to 14.33 ± 3.40 and 15.37 ± 5.85 mmHg in the micropulse- and \"slow cook\" transscleral cyclophotocoagulation groups at the last follow-up, respectively (p=0.110). The mean intraocular pressure reduction at 12 months was 11.20 ± 11.46 and 19.65 ± 13.22 mmHg in the micropulse- and \"slow cook\" transscleral cyclophotocoagulation groups, respectively (p<0.001). The median preoperative logMAR visual acuity was 0.52 ± 0.69 and 1.75 ± 1.04 in the micropulse- and \"slow cook\" transscleral cyclophotocoagulation groups, respectively (p<0.001). The mean visual acuity variation was -0.10 ± 0.35 and -0.074 ± 0.16 in the micropulse- and \"slow cook\" transscleral cyclophotocoagulation, respectively (p=0.510). Preoperatively, the mean eye drops were 3.44 ± 1.38 and 2.89 ± 0.68 drugs in the micropulse- and \"slow cook\" transscleral cyclophotocoagulation groups, respectively (p=0.017), but those were 2.06 ± 1.42 and 1.02 ± 1.46 at the end of the study in the \"slow cook\" and micropulse transscleral cyclophotocoagulation groups, respectively (p<0.001). The success of criterion A was not significant between both groups. Compared with 11 eyes (17.74%) in the \"slow cook\" transscleral cyclophotocoagulation group, 19 eyes (28.78%) in the micropulse transscleral cyclophotocoagulation group showed complete success (p=0.171). For criterion B, 28 (42.42%) and 2 eyes (3.22%) showed complete success after micropulse- and \"slow cook\" transscleral cyclophotocoagulation, respectively (p<0.001).
CONCLUSIONS: Both techniques reduced intraocular pressure effectively.
方法:我们纳入了至少12个月随访的原发性开角型青光眼患者。我们收集并分析了有关术前特征和术后结局的数据。主要结果是基线值降低≥20%(标准A)和/或眼压在6和21mmHg之间(标准B)。
结果:我们纳入了128眼原发性开角型青光眼。经巩膜睫状体光凝组术前平均眼压分别为25.53±6.40和35.02±12.57mmHg,分别(p<0.001)。末次随访时经巩膜睫状体微脉和"慢煮"组平均眼压显著降低至14.33±3.40和15.37±5.85mmHg,分别(p=0.110)。经巩膜睫状体光凝组12个月时平均眼压下降11.20±11.46和19.65±13.22mmHg,分别(p<0.001)。经巩膜睫状体光凝组的术前logMAR视力中位数分别为0.52±0.69和1.75±1.04,分别(p<0.001)。经巩膜睫状体光凝术的平均视力变化为-0.10±0.35和-0.074±0.16,分别(p=0.510)。术前,经巩膜睫状体光凝组的平均滴眼液为3.44±1.38和2.89±0.68药物,分别(p=0.017),但在研究结束时,“慢煮”和微脉冲经巩膜睫状体光凝组分别为2.06±1.42和1.02±1.46,分别(p<0.001)。标准A的成功在两组之间并不显著。与“慢煮”经巩膜睫状体光凝组的11只眼(17.74%)相比,微脉冲经巩膜睫状体光凝组19只眼(28.78%)完全成功(p=0.171)。对于标准B,28只(42.42%)和2只眼(3.22%)在微髓和“慢煮”经巩膜睫状体光凝后显示完全成功,分别(p<0.001)。
结论:两种技术均能有效降低眼压。