UNASSIGNED: In this prospective study, 30 patients scheduled to undergo elective neurosurgery for brain tumor resection were enrolled. Baseline measurements of vitals, anesthetic parameters, and study variables were recorded post-induction. Subsequently, patients received a fluid bolus of 10 mL/kg of colloid over 20 min, and measurements were repeated post-loading. Data were presented as mean ± standard deviation. The normally distributed continuous variables were compared using Student\'s t-test, with P < 0.05 considered statistically significant. The predictive capability of variables for fluid responsiveness was assessed using Pearson\'s coefficient analysis (r).
UNASSIGNED: Of the 30 patients, 22 were identified as volume responders (R), while eight were non-responders (NR). DD >5 mmHg effectively distinguished between R and NR (P < 0.001), with a good predictive ability (r = 0.759). SVCCI >38% differentiated R from NR (P < 0.001), with excellent predictability (r = 0.994). Similarly, VTIAoV >20% was also a good predictor (P < 0.05; r = 0.746).
UNASSIGNED: Our study revealed that most patients undergoing surgical resection of brain tumors exhibited fluid responsiveness. Among the variables assessed, SVCCI >38% emerged as an excellent predictor, followed by VTIAoV >20% and DD >5 mm Hg, for evaluating fluid status in this population.
■在这项前瞻性研究中,纳入了30例计划接受选择性神经外科手术切除脑肿瘤的患者。生命体征的基线测量,麻醉参数,和研究变量在诱导后记录。随后,患者在20分钟内接受了10mL/kg胶体的液体推注,并在加载后重复测量。数据表示为平均值±标准偏差。正态分布的连续变量使用学生t检验进行比较,P<0.05被认为具有统计学意义。使用Pearson系数分析(r)评估变量对液体反应性的预测能力。
■在30名患者中,22人被确定为体积响应者(R),8人是无应答者(NR)。DD>5mmHg有效区分R和NR(P<0.001),具有良好的预测能力(r=0.759)。SVCCI>38%的R与NR(P<0.001),具有良好的可预测性(r=0.994)。同样,VTIAov>20%也是一个很好的预测因子(P<0.05;r=0.746)。
■我们的研究表明,大多数接受脑肿瘤手术切除的患者表现出液体反应性。在评估的变量中,SVCCI>38%是一个很好的预测指标,其次是VTIAoV>20%和DD>5mmHg,用于评估该人群的体液状态。