PDF(Pubmed)
Abstract：
The use of anesthetic agents in the management of fish in fish farming or ornamental fish breeding aims to minimize stress and promote animal welfare. Therefore, this study aims to investigate behavioral, electrocardiographic, and ventilatory characteristics of tambaquis exposed to anesthetic baths with etomidate. The study was conducted with juvenile tambaquis (27.38 ± 3.5g) n = 99, at etomidate concentrations of 2-4 mg.L -1, analyzing induction and anesthetic recovery behavior (experiment I), electrocardiogram (experiment II), and opercular movement (experiment III). Fish exposed to high concentrations of etomidate reached the stage of general anesthesia faster, however, the recovery time was longer, characterizing a dose-dependent relationship. Cardiorespiratory analyzes demonstrated a reduction in heart rate (69.19%) and respiratory rate (40.70%) depending on the concentration of etomidate used during anesthetic induction. During the recovery period, there was cardiorespiratory reversibility to normality. Therefore, etomidate proved to be safe as an anesthetic agent for this species at concentrations of 2 to 3 mg.L -1 for short-term anesthesia, but at higher doses the animals showed slow reversibility of anesthesia in a gradual manner and without excitability. The hemodynamic effect due to the rapid decrease in heart rate includes a negative factor of using higher concentrations of etomidate for Colossome macropomum anesthesia.
摘要：
在鱼类养殖或观赏鱼养殖中的鱼类管理中使用麻醉剂旨在最大程度地减少压力并促进动物福利。因此,这项研究旨在调查行为，心电图,和tambaquis暴露于依托咪酯麻醉浴中的通气特性。该研究使用幼年tambaquis（27.38±3.5g）n=99，依托咪酯浓度为2-4mg。L-1，分析诱导和麻醉恢复行为（实验I），心电图（实验二），和手术运动（实验III）。鱼暴露于高浓度依托咪酯较快地达到全身麻醉阶段，然而,恢复时间较长，表征剂量依赖关系。心脏呼吸分析表明，根据麻醉诱导过程中使用的依托咪酯浓度，心率（69.19％）和呼吸率（40.70％）降低。在恢复期间,心肺可逆性为正常性。因此,事实证明，依托咪酯在2至3mg的浓度下作为该物种的麻醉剂是安全的。短期麻醉的L-1，但是在较高的剂量下，动物以渐进的方式显示出缓慢的麻醉可逆性，并且没有兴奋性。由于心率的快速降低引起的血液动力学效应包括使用较高浓度的依托咪酯用于巨大体眼瘤麻醉的负面因素。
