PDF(Pubmed)
Abstract：
Plant-derived natural compounds are significant resources for the discovery of potential anticancer drugs. While research in the plant-based anticancer field has surged in recent years, systematic bibliometric analyses covering a longer period and containing up-to-date publications remain scarce. Here, we conducted a bibliometric analysis of literature on the anticancer properties of plant natural compounds over the past three decades, leveraging the bibliometric framework and open-access platform, KNIME. Our findings showed that the number of plant anticancer-related publications underwent an accelerating growth from 1992 to 2023. The country and institution analyses revealed that countries with traditional medical systems contributed a large portion of publications in the plant anticancer field, such as India, China, and South Korea. This study also highlighted the top ten eminent researchers and publications, assisting researchers in identifying pivotal literature. The primary publications were domains of chemistry and biology-related fields, such as Pharmacology & Pharmacy, Plant Sciences, and Biochemistry & Molecular Biology. Additionally, we noted that flavonoids have been focal plant compounds in anticancer, with strong anticancer potential. Our study provides new insights into the progress and trends in the plant anticancer field and will assist researchers in grasping the future research direction.
摘要：
植物来源的天然化合物是发现潜在抗癌药物的重要资源。虽然近年来植物抗癌领域的研究激增，涵盖较长时期并包含最新出版物的系统文献计量分析仍然很少。这里,我们对过去三十年来植物天然化合物的抗癌特性进行了文献计量分析，利用文献计量框架和开放获取平台，KNIME.我们的发现表明，从1992年到2023年，与植物抗癌相关的出版物数量加速增长。国家和机构分析显示，拥有传统医疗系统的国家在植物抗癌领域贡献了很大一部分出版物，比如印度,中国,和韩国。这项研究还突出了十大杰出研究人员和出版物，协助研究人员识别关键文献。主要出版物是化学和生物学相关领域，如药理学和药学，植物科学,生物化学和分子生物学。此外,我们注意到类黄酮是抗癌中的主要植物化合物，具有很强的抗癌潜力。我们的研究为植物抗癌领域的进展和趋势提供了新的见解，并将有助于研究人员掌握未来的研究方向。
