Abstract：
OBJECTIVE: To summarize the ultrasonographic features of head and neck Castleman disease (CD), and to clarify its diagnostic key points.
METHODS: Seven patients with head and neck CD confirmed by histopathology were collected from Shanghai Ninth People\'s Hospital, Shanghai Jiao Tong University School of Medicine. The clinical features and ultrasound findings of the patients were evaluated.
RESULTS: Of the 7 patients (1 male and 6 females), the mean age at diagnosis was 31.4 years (7-60 years). All the cases were hyaline vascular type. On ultrasound, 3 lesions (42.9%) were located in the parotid gland, 4 lesions(57.1%) in the neck. All the lesions presented as a solitary, well-defined and solid mass without calcification. The echogenicity was markedly hypoechoic in 1 case(14.3%) and hypoechoic in 6 cases (85.7%). Of the 7 CD cases, 4 cases (57.1%) were heterogeneous masses with linear echogenic septa. All lesions had mixed pattern in vascularity on color Doppler sonography.
CONCLUSIONS: Most CDs in the head and neck represent as a markedly hypoechoic or hypoechoic lesion with mixed pattern in vascularity. The neoplasm may be characterized by the presence of linear echogenic septa within the mass.
METHODS: Seven patients with head and neck CD confirmed by histopathology were collected from Shanghai Ninth People\'s Hospital, Shanghai Jiao Tong University School of Medicine. The clinical features and ultrasound findings of the patients were evaluated.
RESULTS: Of the 7 patients (1 male and 6 females), the mean age at diagnosis was 31.4 years (7-60 years). All the cases were hyaline vascular type. On ultrasound, 3 lesions (42.9%) were located in the parotid gland, 4 lesions(57.1%) in the neck. All the lesions presented as a solitary, well-defined and solid mass without calcification. The echogenicity was markedly hypoechoic in 1 case(14.3%) and hypoechoic in 6 cases (85.7%). Of the 7 CD cases, 4 cases (57.1%) were heterogeneous masses with linear echogenic septa. All lesions had mixed pattern in vascularity on color Doppler sonography.
CONCLUSIONS: Most CDs in the head and neck represent as a markedly hypoechoic or hypoechoic lesion with mixed pattern in vascularity. The neoplasm may be characterized by the presence of linear echogenic septa within the mass.
摘要：
目的：总结头颈部Castleman病（CD）的超声特征，并阐明其诊断要点。
方法：收集7例经组织病理学证实的头颈部CD患者，上海交通大学医学院。评估患者的临床特征和超声检查结果。
结果：在7例患者中（男性1例，女性6例），诊断时的平均年龄为31.4岁(7~60岁).所有病例均为透明血管型。在超声波上，3个病灶(42.9%)位于腮腺,颈部病变4例(57.1%)。所有的病变都是孤立的，明确和坚实的肿块无钙化。回声明显低回声1例(14.3%)，低回声6例(85.7%)。在7个CD案件中，4例（57.1％）为异质肿块，具有线性回声间隔。在彩色多普勒超声检查中，所有病变的血管分布均混合。
结论：头颈部的大多数CD表现为明显的低回声或低回声病变，并伴有血管分布的混合模式。肿瘤的特征可能在于肿块内存在线性回声间隔。
方法：收集7例经组织病理学证实的头颈部CD患者，上海交通大学医学院。评估患者的临床特征和超声检查结果。
结果：在7例患者中（男性1例，女性6例），诊断时的平均年龄为31.4岁(7~60岁).所有病例均为透明血管型。在超声波上，3个病灶(42.9%)位于腮腺,颈部病变4例(57.1%)。所有的病变都是孤立的，明确和坚实的肿块无钙化。回声明显低回声1例(14.3%)，低回声6例(85.7%)。在7个CD案件中，4例（57.1％）为异质肿块，具有线性回声间隔。在彩色多普勒超声检查中，所有病变的血管分布均混合。
结论：头颈部的大多数CD表现为明显的低回声或低回声病变，并伴有血管分布的混合模式。肿瘤的特征可能在于肿块内存在线性回声间隔。
