METHODS: This cross-sectional study was conducted in three periods: pre-opening of the milk bank (PRE) including all women who gave birth to a newborn between January - May 2017 and were hospital users; donors in the first year after the opening (Period 1 (P1): April 2019 - March 2020); and in the second year (P2: April 2020 - March 2021). For P1 and P2, DHM data were recorded. The relationships between donor and newborn characteristics and the donation process were examined using univariable and regression models.
RESULTS: From 391 women interviewed in the PRE period, 55 (14%) showed intention to donate. In P1 and P2, there were 51 and 25 human milk (HM) donors, respectively. Age, gestational age (GA) and parity were similar between periods. In P2, a higher proportion of donors had higher education (P1: 46%; P2: 70.8%, p = 0.045). Around 40% of donors in both periods were on maternity leave. In P1, donors who had low birth weight infants (< 2500 g) donated more HM than those with infants weighing ≥ 2500 g (p = 0.020). In P2, women whose GA was < 37 weeks donated a higher volume vs. those with ≥ 37 weeks (p = 0.002). Maternity leave was linked to a shorter initiation time for donations in both periods (P1: p = 0.002; P2: p < 0.001).
CONCLUSIONS: Data obtained from a Spanish human milk bank indicate that prematurity and low birth weight appear to influence the amounts of DHM. Employment status might be a decisive factor in initiating HM donation. Additional efforts are required to identify shared donor characteristics that influence the initiation and volume of donation.
方法:这项横断面研究分三个阶段进行:牛奶库(PRE)的开业前,包括所有在2017年1月至5月期间分娩的新生儿和医院使用者的妇女;开业后第一年的捐赠者(第1期(P1):2019年4月至2020年3月);第二年(P2:2020年4月至2021年3月)。对于P1和P2,记录DHM数据。使用单变量和回归模型检查了供体和新生儿特征与捐赠过程之间的关系。
结果:来自前一时期接受采访的391名女性,55人(14%)表示有意捐赠。在P1和P2中,有51和25人乳(HM)供体,分别。年龄,不同时期的胎龄(GA)和胎次相似.在P2中,受过高等教育的捐赠者比例更高(P1:46%;P2:70.8%,p=0.045)。在这两个时期,约有40%的捐助者休产假。在P1中,低出生体重婴儿(<2500g)的供体比体重≥2500g的供体捐赠了更多的HM(p=0.020)。在P2中,GA<37周的女性捐赠的量比≥37周的患者(p=0.002)。在这两个时期,产假与较短的捐赠开始时间有关(P1:p=0.002;P2:p<0.001)。
结论:从西班牙人乳库获得的数据表明,早产和低出生体重似乎会影响DHM的含量。就业状况可能是启动HM捐赠的决定性因素。需要额外的努力来确定影响捐赠开始和数量的共同捐赠者特征。