PDF(Pubmed)
Abstract：
Modern human society is burdened with the pandemic of cardiovascular and metabolic diseases. Metrnl is a widely distributed secreted protein in the body, involved in regulating glucose and lipid metabolism and maintaining cardiovascular system homeostasis. In this review, we present the predictive and therapeutic roles of Metrnl in various cardiovascular and metabolic diseases, including atherosclerosis, ischemic heart disease, cardiac remodeling, heart failure, hypertension, chemotherapy-induced myocardial injury, diabetes mellitus, and obesity.
摘要：
现代人类社会承受着心血管疾病和代谢疾病的大流行。Metrnl是一种在体内广泛分布的分泌蛋白,参与调节糖脂代谢和维持心血管系统稳态。在这次审查中,我们介绍了Metrnl在各种心血管和代谢疾病中的预测和治疗作用，包括动脉粥样硬化,缺血性心脏病,心脏重塑,心力衰竭,高血压,化疗引起的心肌损伤,糖尿病,和肥胖。
