METHODS: MEDLINE, EMBASE, Web of Science, the Cochrane database, http://www.
RESULTS: gov , Google Scholar and Mendeley were searched for relevant publications based on COVID-19 patients with NOAF admitted to the ICU. Complications including in-hospital mortality, ICU mortality, patients requiring mechanical ventilation, acute myocardial infarction, acute kidney injury, renal replacement therapy and pulmonary embolism were assessed. This is a meta-analysis and the analytical tool which was used was the RevMan software version 5.4. Risk ratios (RR) and 95% confidence intervals (CIs) were used to represent the data post analysis.
RESULTS: In critically ill COVID-19 patients with NOAF admitted to the ICU, the risks of ICU mortality (RR: 1.39, 95% CI: 1.07 - 1.80; P = 0.01), in-hospital mortality (RR: 1.56, 95% CI: 1.20 - 2.04; P = 0.001), patients requiring mechanical ventilation (RR: 1.32, 95% CI: 1.04 - 1.66; P = 0.02) were significantly higher when compared to the control group without AF. Acute myocardial infarction (RR: 1.54, 95% CI: 1.31 - 1.81; P = 0.00001), the risk for acute kidney injury (RR: 1.31, 95% CI: 1.11 - 1.55; P = 0.002) and patients requiring renal replacement therapy (RR: 1.83, 95% CI: 1.60 - 2.09; P = 0.00001) were also significantly higher in patients with NOAF.
CONCLUSIONS: Critically ill COVID-19 patients with NOAF admitted to the ICU were at significantly higher risks of developing complications and death compared to similar patients without AF.
方法:MEDLINE,EMBASE,WebofScience,Cochrane数据库,http://www。
结果:政府,根据入住ICU的NOAFCOVID-19患者,搜索了GoogleScholar和Mendeley的相关出版物。并发症包括住院死亡率,ICU死亡率,需要机械通气的患者,急性心肌梗死,急性肾损伤,评估了肾脏替代治疗和肺栓塞.这是荟萃分析,使用的分析工具是RevMan软件版本5.4。使用风险比(RR)和95%置信区间(CI)表示分析后的数据。
结果:在入住ICU的重症COVID-19NOAF患者中,ICU死亡风险(RR:1.39,95%CI:1.07-1.80;P=0.01),住院死亡率(RR:1.56,95%CI:1.20-2.04;P=0.001),需要机械通气的患者(RR:1.32,95%CI:1.04-1.66;P=0.02)与无AF的对照组相比,明显较高.急性心肌梗死(RR:1.54,95%CI:1.31-1.81;P=0.00001),急性肾损伤的风险(RR:1.31,95%CI:1.11-1.55;P=0.002)和需要肾脏替代治疗的患者(RR:1.83,95%CI:1.60-2.09;P=0.00001)也显著高于NOAF患者.
结论:入住ICU的患有NOAF的重症COVID-19患者发生并发症和死亡的风险明显高于无AF的类似患者。