Abstract:
Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and function of the previously \'invisible\' parts of the genome and allow comparative analyses of complete genomes across entire clades. We present here an open collaborative effort, termed the \'Ruminant T2T Consortium\' (RT2T), that aims to generate complete diploid assemblies for numerous species of the Artiodactyla suborder Ruminantia to examine chromosomal evolution in the context of natural selection and domestication of species used as livestock.
摘要:
端粒到端粒(T2T)组件揭示了对基因组先前“不可见”部分的结构和功能的新见解,并允许对整个进化枝的完整基因组进行比较分析。我们在这里提出一个开放的合作努力,称为“反刍动物T2T联盟”(RT2T),旨在为Ruminantia的许多物种生成完整的二倍体组装体,以在自然选择和驯化用作牲畜的物种的背景下检查染色体进化。