Abstract：
UNASSIGNED: Sudden infant death syndrome (SIDS) is a tragic and devastating condition whose causes remain largely unknown. Recent studies have shown that the composition of a child\'s gut flora can play a significant role in the development of SIDS.
UNASSIGNED: This work aims to research those factors that influence the composition of the intestinal flora, the role they have in the development of SIDS and the new strategies for preventing SIDS showing a new interpretation through a detailed review of the literature. The gut in physiological conditions is mainly composed of Bacteroidetes, Firmicutes, Actinobacteria, and Proteobacteria, but when there is the presence of dysbiotic or different microbial communities, the onset of the disease is more likely as an altered microbial community can lead to an interruption of the gut-brain axis and an increased risk of SIDS.
UNASSIGNED: All this implies that the composition of the microbiome can be modified to reduce the risk of sudden death in newborns. The results of the literature provide valuable information on the potential role of the intestinal microbiome in SIDS even if not all mechanisms are yet clear, especially in the mechanisms of death. Therefore, it is necessary in cases of SIDS when carrying out an autopsy to also investigate this area; to this end, we suggest a questionnaire to be administered to family members to understand the eating habits of the newborn and the family and integrate with microbiological investigations to explore every possible hypothesis.
UNASSIGNED: This work aims to research those factors that influence the composition of the intestinal flora, the role they have in the development of SIDS and the new strategies for preventing SIDS showing a new interpretation through a detailed review of the literature. The gut in physiological conditions is mainly composed of Bacteroidetes, Firmicutes, Actinobacteria, and Proteobacteria, but when there is the presence of dysbiotic or different microbial communities, the onset of the disease is more likely as an altered microbial community can lead to an interruption of the gut-brain axis and an increased risk of SIDS.
UNASSIGNED: All this implies that the composition of the microbiome can be modified to reduce the risk of sudden death in newborns. The results of the literature provide valuable information on the potential role of the intestinal microbiome in SIDS even if not all mechanisms are yet clear, especially in the mechanisms of death. Therefore, it is necessary in cases of SIDS when carrying out an autopsy to also investigate this area; to this end, we suggest a questionnaire to be administered to family members to understand the eating habits of the newborn and the family and integrate with microbiological investigations to explore every possible hypothesis.
摘要：
■婴儿猝死综合症（SIDS）是一种悲剧性和毁灭性的疾病，其原因在很大程度上仍然未知。最近的研究表明，儿童肠道菌群的组成在SIDS的发展中起着重要作用。
■这项工作旨在研究那些影响肠道菌群组成的因素，它们在发展小岛屿发展中国家中的作用以及预防小岛屿发展中国家的新战略，通过对文献的详细审查，显示出新的解释。生理条件下的肠道主要由拟杆菌组成，Firmicutes,放线菌,和变形杆菌，但是当存在生态失调或不同的微生物群落时，由于微生物群落的改变可导致肠-脑轴的中断和SIDS的风险增加，因此疾病的发作可能性更大。
■所有这些都意味着可以改变微生物组的组成，以降低新生儿猝死的风险。文献的结果提供了有关肠道微生物组在SIDS中的潜在作用的有价值的信息，即使尚未明确所有机制，尤其是死亡机制.因此,在小岛屿发展中国家的情况下，在进行尸检时也有必要调查这一地区；为此，我们建议向家庭成员发放问卷，以了解新生儿和家庭的饮食习惯，并结合微生物学调查，探索每一个可能的假设。
■这项工作旨在研究那些影响肠道菌群组成的因素，它们在发展小岛屿发展中国家中的作用以及预防小岛屿发展中国家的新战略，通过对文献的详细审查，显示出新的解释。生理条件下的肠道主要由拟杆菌组成，Firmicutes,放线菌,和变形杆菌，但是当存在生态失调或不同的微生物群落时，由于微生物群落的改变可导致肠-脑轴的中断和SIDS的风险增加，因此疾病的发作可能性更大。
■所有这些都意味着可以改变微生物组的组成，以降低新生儿猝死的风险。文献的结果提供了有关肠道微生物组在SIDS中的潜在作用的有价值的信息，即使尚未明确所有机制，尤其是死亡机制.因此,在小岛屿发展中国家的情况下，在进行尸检时也有必要调查这一地区；为此，我们建议向家庭成员发放问卷，以了解新生儿和家庭的饮食习惯，并结合微生物学调查，探索每一个可能的假设。
