PDF(Pubmed)
Abstract：
UNASSIGNED: Women with schizophrenia have a high risk of adverse sexual health outcomes. The chronic course of schizophrenia draws attention to assessing the quality of life and marital relationships of patients with schizophrenia. However, there is a crunch of data in the Indian setting. This study aimed to investigate the prevalence of sexual dysfunctions (SDs) and determine the marital relationship and quality of life among women with schizophrenia.
UNASSIGNED: The study followed an analytical case-control design. The study was conducted at the inpatient psychiatric department of one of the apex tertiary healthcare centers located at the foothills of the Northern Himalayas. The study purposively included 136 participants (68 cases and 68 controls). The control group included healthy women aged 18-45 currently staying with sexual partners. Data were collected using pretested and standardized self-report questionnaires.
UNASSIGNED: The median age of the case group was 36 (interquartile range (IQR), 29-42) years, while that of the control group was 29 (IQR 26-34) years. The prevalence of SD was significantly higher (P = 0.001) in cases (95.3%) than in controls (73.4%). Compared to healthy controls, women with schizophrenia have a significantly higher rate of SD in sexual desire (P = 0.001), getting arousal (P < 0.001), lubrication (P < 0.001), achieving orgasm (P < 0.001), and sexual satisfaction (P < 0.001) (except pain). In addition, the marital relationship was better managed (P < 0.001) in healthy controls compared with cases. The healthy control group significantly expressed a better quality of life in physical (P < 0.001), psychological (P < 0.001), and maintaining social (P < 0.001) relationships (except environment domains). In multivariable logistic regression analysis, employment status significantly predicted SDs (odds ratio (OR), 25.78; 95% confidence interval (CI), 2.09, 318.10; P < 0.05) in participants.
UNASSIGNED: The prevalence of SD is significantly high among female participants. Hence, treating physicians should pay attention to sexual function during the screening and treatment of patients with schizophrenia.
UNASSIGNED: The study followed an analytical case-control design. The study was conducted at the inpatient psychiatric department of one of the apex tertiary healthcare centers located at the foothills of the Northern Himalayas. The study purposively included 136 participants (68 cases and 68 controls). The control group included healthy women aged 18-45 currently staying with sexual partners. Data were collected using pretested and standardized self-report questionnaires.
UNASSIGNED: The median age of the case group was 36 (interquartile range (IQR), 29-42) years, while that of the control group was 29 (IQR 26-34) years. The prevalence of SD was significantly higher (P = 0.001) in cases (95.3%) than in controls (73.4%). Compared to healthy controls, women with schizophrenia have a significantly higher rate of SD in sexual desire (P = 0.001), getting arousal (P < 0.001), lubrication (P < 0.001), achieving orgasm (P < 0.001), and sexual satisfaction (P < 0.001) (except pain). In addition, the marital relationship was better managed (P < 0.001) in healthy controls compared with cases. The healthy control group significantly expressed a better quality of life in physical (P < 0.001), psychological (P < 0.001), and maintaining social (P < 0.001) relationships (except environment domains). In multivariable logistic regression analysis, employment status significantly predicted SDs (odds ratio (OR), 25.78; 95% confidence interval (CI), 2.09, 318.10; P < 0.05) in participants.
UNASSIGNED: The prevalence of SD is significantly high among female participants. Hence, treating physicians should pay attention to sexual function during the screening and treatment of patients with schizophrenia.
摘要：
患有精神分裂症的女性有很高的性健康不良结局的风险。精神分裂症的慢性过程引起了人们对评估精神分裂症患者的生活质量和婚姻关系的关注。然而,在印度的背景下有大量的数据。本研究旨在调查精神分裂症女性性功能障碍（SDs）的患病率，并确定其婚姻关系和生活质量。
■该研究遵循分析病例对照设计。这项研究是在位于喜马拉雅山北部山麓的顶级三级医疗中心之一的住院精神科进行的。该研究有目的地包括136名参与者（68例病例和68名对照）。对照组包括目前与性伴侣在一起的18-45岁健康女性。使用预先测试和标准化的自我报告问卷收集数据。
■病例组的中位年龄为36岁（四分位距（IQR），29-42）年，而对照组为29年（IQR26-34）。病例（95.3%）的SD患病率明显高于对照组（73.4%）（P=0.001）。与健康对照相比，女性精神分裂症患者的性欲SD率明显较高（P=0.001），得到唤醒（P<0.001），润滑（P<0.001），达到性高潮（P<0.001），和性满意度（P<0.001）（疼痛除外）。此外,与病例相比，健康对照组的婚姻关系得到了更好的管理（P<0.001）。健康对照组在体格上有较好的生活质量(P<0.001),心理（P<0.001），并维持社会关系(P<0.001)(环境领域除外)。在多变量逻辑回归分析中，就业状况显著预测SDs(优势比(OR)，25.78；95%置信区间(CI)，2.09，318.10；P<0.05）。
■女性参与者中SD的患病率明显较高。因此，在精神分裂症患者的筛查和治疗过程中，医生应注意性功能。
■该研究遵循分析病例对照设计。这项研究是在位于喜马拉雅山北部山麓的顶级三级医疗中心之一的住院精神科进行的。该研究有目的地包括136名参与者（68例病例和68名对照）。对照组包括目前与性伴侣在一起的18-45岁健康女性。使用预先测试和标准化的自我报告问卷收集数据。
■病例组的中位年龄为36岁（四分位距（IQR），29-42）年，而对照组为29年（IQR26-34）。病例（95.3%）的SD患病率明显高于对照组（73.4%）（P=0.001）。与健康对照相比，女性精神分裂症患者的性欲SD率明显较高（P=0.001），得到唤醒（P<0.001），润滑（P<0.001），达到性高潮（P<0.001），和性满意度（P<0.001）（疼痛除外）。此外,与病例相比，健康对照组的婚姻关系得到了更好的管理（P<0.001）。健康对照组在体格上有较好的生活质量(P<0.001),心理（P<0.001），并维持社会关系(P<0.001)(环境领域除外)。在多变量逻辑回归分析中，就业状况显著预测SDs(优势比(OR)，25.78；95%置信区间(CI)，2.09，318.10；P<0.05）。
■女性参与者中SD的患病率明显较高。因此，在精神分裂症患者的筛查和治疗过程中，医生应注意性功能。
