Abstract：
The overuse of antibiotics and antitumor drugs has resulted in more and more extensive pollution of water bodies with organic drugs, causing detrimental ecological effects, which have attracted attention towards effective and sustainable methods for antibiotics and antitumor drug degradation. Here, the hybrid nanomaterial (g-C3N4@Fe/Pd) was synthesized and used to remove a kind of both an antibiotic and antitumor drug named mitoxantrone (MTX) with 92.0% removal efficiency, and the MTX removal capacity is 450 mg/g. After exposing to the hybrid material the MTX aqueous solution changed color from dark blue to lighter progressively, and LC-UV results of residual solutions show that a new peak at 3.0 min (MTX: 13.2 min) after removal by g-C3N4@Fe/Pd appears, with the simultaneous detection of intermediate products indicating that g-C3N4@Fe/Pd indeed degrades MTX. Detailed mass spectrometric analysis suggests that the nuclear mass ratio decreased from 445.2 (M+1H) to 126.0 (M+1H), 169.1 (M+1H), 239.2 (M+1H), 267.3 (M+1H), 285.2 (M+1H), 371.4 (M+1H) and 415.2 (M+1H), and the maximum proportion (5.63%) substance of all degradation products (126.0 (M+1H)) is 40-100 times less toxic than MTX. A mechanism for the removal and degradation of mitoxantrone was proposed. Besides, actual water experiments confirmed that the maximum removal capacity of MTX by g-C3N4@Fe/Pd is up to 492.4 mg/g (0.02 g/L, 10 ppm).
摘要：
抗生素和抗肿瘤药物的过度使用导致有机药物对水体的污染越来越广泛,造成有害的生态影响，抗生素和抗肿瘤药物降解的有效和可持续方法引起了人们的关注。这里,合成了杂化纳米材料(g-C3N4@Fe/Pd)，并用于去除一种名为米托蒽醌(MTX)的抗生素和抗肿瘤药物，去除率为92.0%，MTX去除能力为450mg/g。暴露于混合材料后，MTX水溶液逐渐从深蓝色变为较浅，和残留溶液的LC-UV结果表明，在用g-C3N4@Fe/Pd去除后，在3.0分钟（MTX：13.2分钟）出现新峰，中间产物的同时检测表明g-C3N4@Fe/Pd确实降解MTX。详细的质谱分析表明，核质量比从445.2(M+1H)下降到126.0(M+1H)，169.1(M+1H),239.2(M+1H),267.3(M+1H),285.2(M+1H),371.4(M+1H)和415.2(M+1H)，所有降解产物(126.0(M+1H))的最大比例(5.63%)是MTX毒性的40-100倍。提出了去除和降解米托蒽醌的机理。此外,实际水实验证实，g-C3N4@Fe/Pd对MTX的最大去除能力高达492.4mg/g（0.02g/L，10ppm)。
