Abstract：
This article summarizes the current evidence regarding inflammatory biomarkers (placental and postnatal) and provides a comprehensive understanding of their roles: (1) diagnostic accuracy to predict the severity of hypoxic-ischemia encephalopathy (HIE), (2) value in assessing treatment responses, and (3) prediction of both short- and long-term neurodevelopmental outcomes. In the early critical stages of perinatal asphyxia, inflammatory biomarkers may guide clinical decision-making. Additional research is required to increase our understanding of the optimal utility of biomarkers to predict the severity, evolution, and developmental outcomes after exposure to HIE.
摘要：
本文总结了目前有关炎症生物标志物（胎盘和产后）的证据，并提供了对其作用的全面理解：（1）预测缺氧缺血性脑病（HIE）严重程度的诊断准确性，(2)评估治疗反应的价值，（3）预测短期和长期神经发育结果。在围产期窒息的早期关键阶段，炎性生物标志物可指导临床决策.需要额外的研究来增加我们对生物标志物预测严重程度的最佳效用的理解。进化,暴露于HIE后的发育结果。
