Mesh : Humans Male Female Risk Factors Prospective Studies Vertebral Artery Dissection / complications diagnostic imaging Middle Aged Adult Cerebral Infarction / diagnostic imaging etiology Carotid Artery, Internal, Dissection / complications diagnostic imaging Time Factors Sex Factors Aged

来  源:   DOI:10.4067/s0034-98872023001001281

Abstract:
BACKGROUND: Cervical artery dissections (CAD) are the leading cause of ischemic stroke (CVA) in young people. The risk factors for stroke and the temporal relationship with CAD are not well characterized. Nor do we have a clinical-radiological classification that allows knowing the risk of stroke.
OBJECTIVE: To describe the associated factors and temporality of ACVi in patients with CAD.
METHODS: We performed a prospective study that included patients over 18 years of age, hospitalized for carotid and/or vertebral CAD between August 2009 and June 2017. CAD cases were diagnosed clinically and radiologically; ACVi was diagnosed when the imaging study demonstrated infarction. The Borgess Classification was used to characterize the CAD radiologically. For correlation studies, we used univariate and multivariate logistic regression analyses.
RESULTS: We analyzed 163 patients with 182 CAD (60% vertebral and 40% carotid). 28 of 68 patients (41.2%) simultaneously had symptoms of dissection and ischemia. 60 of 68 patients (88%) presented symptoms of ischemia during the first week. CAD: Borgess type IB (p = 0.001; OR: 4.1; CI: 1.8-9.3), male (p < 0.001; OR: 0.2; CI: 0.06- 0.8) were significantly associated with ischemic strokes and oral contraceptives (p = 0.02; OR: 0.2; CI: 0.06-0.8).
CONCLUSIONS: Stroke associated with CAD has a relatively low frequency. It is not related to the type of dissected artery. It mainly occurs not simultaneously with CAD and within the first week. The main associated factor for developing a stroke is arterial occlusion (Borgess type IB).1,8-9,3), male sex (p < 0.001; OR: 0.2; CI: 0.06-0.8) and oral contraceptives (p = 0.02; OR: 0.2; CI: 0.06-0.8).
摘要:
背景:颈动脉夹层(CAD)是年轻人缺血性卒中(CVA)的主要原因。中风的危险因素和与CAD的时间关系没有很好的表征。我们也没有允许了解中风风险的临床放射学分类。
目的:描述CAD患者ACVi的相关因素和时间性。
方法:我们进行了一项前瞻性研究,包括18岁以上的患者,2009年8月至2017年6月期间因颈动脉和/或椎体CAD住院。临床和放射学诊断为CAD病例;当影像学研究显示梗塞时,诊断为ACVi。Borgess分类用于在放射学上表征CAD。对于相关性研究,我们使用单变量和多变量逻辑回归分析.
结果:我们分析了163例182例CAD患者(60%椎体和40%颈动脉)。68例患者中有28例(41.2%)同时出现夹层和缺血症状。68例患者中有60例(88%)在第一周出现缺血症状。CAD:BorgessIB型(p=0.001;OR:4.1;CI:1.8-9.3),男性(p<0.001;OR:0.2;CI:0.06-0.8)与缺血性卒中和口服避孕药显著相关(p=0.02;OR:0.2;CI:0.06-0.8).
结论:与CAD相关的卒中频率相对较低。它与解剖动脉的类型无关。它主要不与CAD同时发生并且在第一周内发生。发生中风的主要相关因素是动脉闭塞(BorgessIB型).1,8-9,3),男性(p<0.001;OR:0.2;CI:0.06-0.8)和口服避孕药(p=0.02;OR:0.2;CI:0.06-0.8)。
公众号