关键词: cerebral malaria cognitive impairment malaria malaria morbidity mental health neurocognition neurological impairment

来  源:   DOI:10.3389/fnhum.2024.1432441   PDF(Pubmed)

Abstract:
Malaria morbidity has various presentations and the focus now shifts to uncommon signs and symptoms of malaria infection such as cognitive impairment to address the morbidity when the mortality declines. About 50% of children admitted to hospitals due to malaria experience neurological complications due to factors like low blood sugar, inflammation, elevated pressure, decreased oxygen levels, and excitotoxicity. Malaria during pregnancy negatively also impacts children\'s cognitive, behavioral, and executive function leading to neurodevelopmental delay due to increased susceptibility which can significantly affect maternal and child health, leading to higher rates of underestimated factors like anxiety, depression, and PTSD. Despite having the world\'s second-largest tribal population, India\'s indigenous and tribal communities and their mental health are less explored and less understood. Western psychological tools and neurocognitive assessment tools are not universally applicable, thus necessitating the development of tailored tools to investigate psychological or neurocognitive impairment. This paper has illuminated the hidden mental health consequences of malaria infection, emphasizing the prevalence, nature, and implications of psychological distress among affected individuals. The findings underscore the importance of recognizing and addressing these psychological consequences in the holistic management and prevention of malaria and its mental health consequences.
摘要:
疟疾发病率有各种表现,现在的重点转移到疟疾感染的罕见体征和症状,例如认知障碍,以解决死亡率下降时的发病率。大约50%因疟疾入院的儿童由于低血糖等因素而出现神经系统并发症,炎症,压力升高,氧气水平降低,和兴奋毒性。怀孕期间的疟疾也会对儿童的认知产生负面影响,行为,和执行功能导致神经发育迟缓,由于增加的易感性,可以显着影响母婴健康,导致焦虑等被低估因素的发生率更高,抑郁症,PTSD尽管拥有世界第二大部落人口,印度的土著和部落社区和他们的心理健康很少被探索和了解。西方心理学工具和神经认知评估工具并不普遍适用,因此,有必要开发量身定制的工具来研究心理或神经认知障碍。本文阐明了疟疾感染的潜在心理健康后果,强调患病率,自然,以及受影响个体心理困扰的影响。调查结果强调了在全面管理和预防疟疾及其心理健康后果方面认识和解决这些心理后果的重要性。
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