PDF(Pubmed)
Abstract：
Prior research highlights that rural populations have been historically underrepresented/excluded from clinical research. The primary objective of this study was to describe the inclusion of rural populations within our research enterprise using Clinical Research Management System demographic information at a large academic medical center in the Southeast. This was a cross-sectional study using participant demographic information for all protocols entered into our Clinical Research Management System between May 2018 and March 2021. Descriptive statistics were used to analyze the representation of rural and non-rural participants and demographic breakdown by age, sex, race, and ethnicity for our entire enterprise and at the state level. We also compared Material Community Deprivation Index levels between urban and rural participants. Results indicated that 19% of the research population was classified as rural and 81% as non-rural for our entire sample, and 17.5% rural and 82.5% urban for our state-level sample. There were significant differences in race, sex, and age between rural and non-rural participants and Material Community Deprivation Indices between rural and non-rural participants. Lessons learned and recommendations for increasing the inclusion of rural populations in research are discussed.
摘要：
先前的研究强调，农村人口历来被低估/排除在临床研究之外。这项研究的主要目的是使用东南部大型学术医学中心的临床研究管理系统人口统计学信息来描述我们研究企业中农村人口的纳入情况。这是一项横断面研究，使用2018年5月至2021年3月期间进入我们临床研究管理系统的所有方案的参与者人口统计学信息。描述性统计数据用于分析农村和非农村参与者的代表性以及按年龄划分的人口统计，性别,种族,以及我们整个企业和州一级的种族。我们还比较了城乡参与者的物质社区剥夺指数水平。结果表明，在我们整个样本中，19%的研究人群被归类为农村，81%被归类为非农村。我们的国家级样本为17.5%的农村和82.5%的城市。种族有显著差异，性别,农村和非农村参与者之间的年龄以及农村和非农村参与者之间的物质社区剥夺指数。讨论了有关增加农村人口参与研究的经验教训和建议。
