PDF(Pubmed)
Abstract：
UNASSIGNED: Studies have reported conflicting findings on the relationship between smoking and surgical site infection (SSI) post fixation for ankle and calcaneal fractures. This meta-analysis explored the effect of smoking on SSI incidence following open reduction and internal fixation (ORIF) of these fractures.
UNASSIGNED: Full-text studies on smoking\'s influence on post-ORIF SSI rates for closed ankle and calcaneal fractures were sourced from the PubMed, Embase, and Cochrane databases, with no consideration given to language or publication date. Study quality was appraised using the Newcastle-Ottawa Scale. Odds ratios (OR) and the corresponding 95% CIs were determined using random-effects models. This meta-analysis adhered to the PRISMA guidelines and was registered with PROSPERO (CRD42023429372).
UNASSIGNED: The analysis incorporated data from 16 cohort and case-control studies, totaling 41 944 subjects, 9984 of whom were smokers, with 956 SSI cases. Results indicated smokers faced a higher SSI risk (OR: 1.62; 95% CI: 1.32-1.97, P < 0.0001) post ORIF, with low heterogeneity (I 2 = 26%). Smoking was identified as a significant deep SSI risk factor (OR: 2.09; 95% CI: 1.42-3.09; P = 0.0002; I 2 = 31%). However, the subgroup analysis revealed no association between smoking and superficial SSI (OR: 1.05; 95% CI: 0.82-1.33; P = 0.70; I 2 = 0%).
UNASSIGNED: Smoking is associated with increased SSI risk after ORIF for closed ankle and calcaneus fractures. Although no clear link was found between superficial SSI and smoking, the data underscore the negative influence of smoking on deep SSI incidence.
UNASSIGNED: Full-text studies on smoking\'s influence on post-ORIF SSI rates for closed ankle and calcaneal fractures were sourced from the PubMed, Embase, and Cochrane databases, with no consideration given to language or publication date. Study quality was appraised using the Newcastle-Ottawa Scale. Odds ratios (OR) and the corresponding 95% CIs were determined using random-effects models. This meta-analysis adhered to the PRISMA guidelines and was registered with PROSPERO (CRD42023429372).
UNASSIGNED: The analysis incorporated data from 16 cohort and case-control studies, totaling 41 944 subjects, 9984 of whom were smokers, with 956 SSI cases. Results indicated smokers faced a higher SSI risk (OR: 1.62; 95% CI: 1.32-1.97, P < 0.0001) post ORIF, with low heterogeneity (I 2 = 26%). Smoking was identified as a significant deep SSI risk factor (OR: 2.09; 95% CI: 1.42-3.09; P = 0.0002; I 2 = 31%). However, the subgroup analysis revealed no association between smoking and superficial SSI (OR: 1.05; 95% CI: 0.82-1.33; P = 0.70; I 2 = 0%).
UNASSIGNED: Smoking is associated with increased SSI risk after ORIF for closed ankle and calcaneus fractures. Although no clear link was found between superficial SSI and smoking, the data underscore the negative influence of smoking on deep SSI incidence.
摘要：
■研究报告了关于吸烟与踝关节和跟骨骨折固定后手术部位感染（SSI）之间关系的矛盾发现。这项荟萃分析探讨了吸烟对这些骨折切开复位内固定（ORIF）后SSI发生率的影响。
■关于吸烟对闭合性踝关节和跟骨骨折的ORIF后SSI率影响的全文研究来源于PubMed，Embase,和Cochrane数据库，不考虑语言或出版日期。使用纽卡斯尔-渥太华量表评估研究质量。使用随机效应模型确定赔率(OR)和相应的95%CI。该荟萃分析遵循PRISMA指南，并在PROSPERO（CRD42023429372）注册。
■分析纳入了来自16项队列和病例对照研究的数据，共41944个科目,其中9984人是吸烟者，956例SSI病例。结果表明，吸烟者在ORIF后面临更高的SSI风险（OR：1.62;95％CI：1.32-1.97，P<0.0001），异质性低(I2=26%)。吸烟被确定为一个显著的深度SSI危险因素(OR:2.09;95%CI:1.42-3.09;P=0.0002;I2=31%)。然而,亚组分析显示吸烟与浅表SSI无相关性(OR:1.05;95%CI:0.82~1.33;P=0.70;I2=0%).
吸烟与闭合性踝关节和跟骨骨折ORIF后SSI风险增加相关。虽然没有发现明显的联系在肤浅的SSI和吸烟之间，数据强调了吸烟对深SSI发生率的负面影响.
■关于吸烟对闭合性踝关节和跟骨骨折的ORIF后SSI率影响的全文研究来源于PubMed，Embase,和Cochrane数据库，不考虑语言或出版日期。使用纽卡斯尔-渥太华量表评估研究质量。使用随机效应模型确定赔率(OR)和相应的95%CI。该荟萃分析遵循PRISMA指南，并在PROSPERO（CRD42023429372）注册。
■分析纳入了来自16项队列和病例对照研究的数据，共41944个科目,其中9984人是吸烟者，956例SSI病例。结果表明，吸烟者在ORIF后面临更高的SSI风险（OR：1.62;95％CI：1.32-1.97，P<0.0001），异质性低(I2=26%)。吸烟被确定为一个显著的深度SSI危险因素(OR:2.09;95%CI:1.42-3.09;P=0.0002;I2=31%)。然而,亚组分析显示吸烟与浅表SSI无相关性(OR:1.05;95%CI:0.82~1.33;P=0.70;I2=0%).
吸烟与闭合性踝关节和跟骨骨折ORIF后SSI风险增加相关。虽然没有发现明显的联系在肤浅的SSI和吸烟之间，数据强调了吸烟对深SSI发生率的负面影响.
