Abstract：
Vitiligo is a chronic depigmenting disorder that significantly impacts the quality of life of patients. Though there have been significant advancements in targeted therapies in skin diseases such as psoriasis or eczema, the progress in the treatment of vitiligo has been slow, with minimal studies assessing the effect of biologics, though there has been recent evidence of the effectiveness of JAK inhibition. This paper reviews the published case reports and studies for the use of systemic targeted therapies including biologics and JAK inhibitors in vitiligo.
摘要：
白癜风是一种慢性色素脱失障碍，显著影响患者的生活质量。尽管在牛皮癣或湿疹等皮肤病的靶向治疗方面取得了重大进展，白癜风的治疗进展缓慢,很少有研究评估生物制剂的效果，尽管最近有证据表明JAK抑制的有效性。本文回顾了已发表的病例报告和在白癜风中使用包括生物制剂和JAK抑制剂在内的全身靶向治疗的研究。
