Abstract：
Objectives: This secondary analysis examined five facets of mindful awareness as potential moderators of clinical outcomes using data from a randomized controlled trial (RCT) that compared Mantram Repetition Program (MRP) with present-centered therapy (PCT) in veterans with post-traumatic stress disorder (PTSD). Methods: Data were examined from 173 veterans with military-related PTSD randomly assigned to receive eight sessions of MRP (n = 89) or PCT (n = 84). Clinician-administered and self-report measures of mindfulness (Five Facet Mindfulness Questionnaire [FFMQ]), PTSD severity, insomnia symptoms, and depression symptoms, and were obtained pre- and post-intervention. Hierarchical regressions were used to test for FFMQ moderation on clinical outcomes within the two treatment groups. Results: For those with greater ability to \"describe their internal experience\" (+1 standard deviation [SD]), MRP was associated with lower PTSD hyperarousal symptoms post-intervention than PCT (p < 0.001). For those with lower \"nonreactivity to internal stimuli\" (-1 SD), MRP was associated with greater reductions in PTSD avoidance and numbing symptoms and insomnia compared with PCT (all ps < 0.002). Conclusions: Pre-intervention mindfulness domains of \"describe\" and \"nonreactivity to inner experience\" differentially predicted improvements in PTSD and insomnia symptoms for MRP as compared with PCT subjects. The FFMQ may be an important tool for predicting patient preparedness for mindfulness-based interventions, such as MRP.
摘要：
目标：这项次要分析使用来自随机对照试验（RCT）的数据，将Mantram重复计划（MRP）与以当前为中心的治疗（PCT）在创伤后退伍军人中进行比较，检查了作为临床结果潜在调节者的正念意识的五个方面压力障碍（PTSD）。方法：从173名与军事相关的创伤后应激障碍的退伍军人中收集数据，随机分配接受8次MRP（n=89）或PCT（n=84）。临床医生管理和自我报告的正念措施（五方面正念问卷[FFMQ]），创伤后应激障碍严重程度,失眠症状,和抑郁症状，并在干预前后获得。分层回归用于测试FFMQ对两个治疗组的临床结果的适度。结果：对于那些“描述他们的内部经验”能力更强的人（+1个标准差[SD]），MRP与干预后的PTSD过度觉醒症状低于PCT相关（p<0.001）。对于那些“对内部刺激不反应性”较低的人（-1SD），与PCT相比，MRP与PTSD回避和麻木症状以及失眠的减少有关（所有ps<0.002）。结论：与PCT受试者相比，“描述”和“对内部经验的非反应性”的干预前正念域差异预测了MRP的PTSD和失眠症状的改善。FFMQ可能是预测患者对基于正念的干预的准备的重要工具，比如MRP。
