PDF(Pubmed)
Abstract：
Neuromuscular diseases (NMDs) comprise a heterogeneous group of conditions characterized by extreme progressive muscle weakness leading to respiratory failure. Noninvasive mechanical ventilation (NIV) has emerged as a cornerstone in the management of respiratory complications associated with NMDs. This review aims to elucidate the role of NMV in respiratory function, improving quality of life, and prolonging survival in individuals with NMD. The physiological basis of respiratory impairment in NMDs, principles of NMV application, evidence supporting its efficacy, patient selection criteria, and potential challenges in its application are discussed.
摘要：
神经肌肉疾病(NMD)包括一组异质性病症,其特征在于导致呼吸衰竭的极度进行性肌无力。无创机械通气（NIV）已成为与NMD相关的呼吸系统并发症管理的基石。本文旨在阐明NMV在呼吸功能中的作用。提高生活质量,延长NMD患者的生存期。NMD呼吸损害的生理基础，NMV应用原理，支持其功效的证据，患者选择标准，并讨论了其应用中的潜在挑战。
