Abstract：
BACKGROUND: Primary cutaneous lymphomas are a distinct group of rare lymphoid neoplasms with absence of extracutaneous lymphomas at the time of presentation. They are rare in Nepal and no data on cutaneous lymphoma have been published from this country till date.
METHODS: This retrospective study included 15 cases of cutaneous lymphomas retrieved from the records of department of Dermatopathology, DI Skin Hospital and Referral Centre, Bansbari, Kathmandu, Nepal. Patients were diagnosed according to the current WHO classification for cutaneous lymphoma.
RESULTS: A total of 15 cases were studied with median age of 45 years (range: 22 to 81 years) and male to female ratio of 1.5:1. Primary cutaneous lymphomas constituted 13 cases out of 15 and the most common type of cutaneous lymphoma was mycosis fungoides and variants 5 (33%), followed by CD30 positive primary cutaneous anaplastic large cell lymphoma constituting 2 (13%). T-cell cutaneous lymphoma constituted 13 (87%) and B-cell cutaneous lymphoma 2 (13%).
CONCLUSIONS: Cutaneous T-cell lymphomas were more frequent than cutaneous B-cell lymphomas in Nepalese patients. Mycosis fungoides and variants are commonest type of primary cutaneous lymphomas.
METHODS: This retrospective study included 15 cases of cutaneous lymphomas retrieved from the records of department of Dermatopathology, DI Skin Hospital and Referral Centre, Bansbari, Kathmandu, Nepal. Patients were diagnosed according to the current WHO classification for cutaneous lymphoma.
RESULTS: A total of 15 cases were studied with median age of 45 years (range: 22 to 81 years) and male to female ratio of 1.5:1. Primary cutaneous lymphomas constituted 13 cases out of 15 and the most common type of cutaneous lymphoma was mycosis fungoides and variants 5 (33%), followed by CD30 positive primary cutaneous anaplastic large cell lymphoma constituting 2 (13%). T-cell cutaneous lymphoma constituted 13 (87%) and B-cell cutaneous lymphoma 2 (13%).
CONCLUSIONS: Cutaneous T-cell lymphomas were more frequent than cutaneous B-cell lymphomas in Nepalese patients. Mycosis fungoides and variants are commonest type of primary cutaneous lymphomas.
摘要：
背景：原发性皮肤淋巴瘤是一组独特的罕见淋巴样肿瘤，在出现时没有皮肤外淋巴瘤。它们在尼泊尔很少见，迄今为止，该国尚未发布有关皮肤淋巴瘤的数据。
方法：这项回顾性研究包括从皮肤病理学记录中检索的15例皮肤淋巴瘤，DI皮肤医院及转诊中心，班斯巴里,加德满都,尼泊尔。根据目前的WHO皮肤淋巴瘤分类诊断患者。
结果：共研究了15例病例，中位年龄为45岁（范围：22至81岁），男女比例为1.5：1。原发性皮肤淋巴瘤占15例中的13例，最常见的皮肤淋巴瘤类型是真菌病和变异型5（33％）。其次是CD30阳性的原发性皮肤间变性大细胞淋巴瘤构成2（13％）。T细胞皮肤淋巴瘤占13（87％），B细胞皮肤淋巴瘤占2（13％）。
结论：尼泊尔患者皮肤T细胞淋巴瘤比皮肤B细胞淋巴瘤更常见。真菌病和变种是最常见的原发性皮肤淋巴瘤类型。
方法：这项回顾性研究包括从皮肤病理学记录中检索的15例皮肤淋巴瘤，DI皮肤医院及转诊中心，班斯巴里,加德满都,尼泊尔。根据目前的WHO皮肤淋巴瘤分类诊断患者。
结果：共研究了15例病例，中位年龄为45岁（范围：22至81岁），男女比例为1.5：1。原发性皮肤淋巴瘤占15例中的13例，最常见的皮肤淋巴瘤类型是真菌病和变异型5（33％）。其次是CD30阳性的原发性皮肤间变性大细胞淋巴瘤构成2（13％）。T细胞皮肤淋巴瘤占13（87％），B细胞皮肤淋巴瘤占2（13％）。
结论：尼泊尔患者皮肤T细胞淋巴瘤比皮肤B细胞淋巴瘤更常见。真菌病和变种是最常见的原发性皮肤淋巴瘤类型。
