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Abstract：
High myopia can lead to pathologic myopia and visual impairment, whereas its causes are unclear. We retrospectively researched high myopia cases from patient records to investigate the association between axial elongation and myopic maculopathy. Sixty-four eyes were examined in patients who visited the department between July 2017 and June 2018, had an axial length of 26 mm or more, underwent fundus photography, and had their axial length measured twice or more. The average axial length was 28.29 ± 1.69 mm (mean ± standard deviation). The average age was 58.3 ± 14.4 years old. Myopic maculopathy was categorized as mild (grades 0 and 1) and severe (grades 2, 3, and 4). The severe group had longer axial lengths than the mild group (P < 0.05). Moreover, the severe group exhibited thinner choroidal thickness than the mild group (P < 0.05). When subjects were grouped by axial elongation over median value within a year, the elongation group showed thinner central choroidal thickness than the non-elongation group (142.1 ± 91.9 vs. 82.9 ± 69.8, P < 0.05). In conclusion, in patients with high myopia, the severity of maculopathy correlated with choroidal thickness and axial length. Thinner choroidal thickness was associated with axial elongation based on the baseline axial length.
摘要：
高度近视可导致病理性近视和视觉障碍，而其原因尚不清楚。我们从患者记录中回顾性研究了高度近视病例，以研究轴向伸长与近视性黄斑病变之间的关系。在2017年7月至2018年6月期间访问该部门的患者中检查了64只眼，轴长为26毫米或更多，做了眼底照相,并且测量了它们的轴向长度两次或更多。平均轴向长度为28.29±1.69mm(平均值±标准偏差)。平均年龄58.3±14.4岁。近视性黄斑病变分为轻度（0级和1级）和重度（2级、3级和4级）。重度组的轴向长度长于轻度组（P<0.05）。此外，重度组脉络膜厚度较轻度组薄(P<0.05)。当受试者在一年内按轴向伸长率超过中位值分组时，伸长组中心脉络膜厚度比非伸长组(142.1±91.9vs.82.9±69.8,P<0.05)。总之,在高度近视患者中，黄斑病变的严重程度与脉络膜厚度和眼轴长度有关。较薄的脉络膜厚度与基于基线轴向长度的轴向伸长相关。
