CRISPR - CasRx 介导的 Aqp1 / Adrb2 / Rock1 / Rock2 基因破坏可降低小鼠眼内压和视网膜神经节细胞损伤。
Mesh : Animals Retinal Ganglion Cells / metabolism pathology rho-Associated Kinases / metabolism genetics Intraocular Pressure Female Aquaporin 1 / metabolism genetics Mice Glaucoma / genetics metabolism CRISPR-Cas Systems Aqueous Humor / metabolism Mice, Inbred C57BL Disease Models, Animal RNA Interference Humans
来 源:
DOI:10.1038/s41467-024-50050-4
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