Abstract：
The TEC (tyrosine kinase expressed in hepatocellular carcinoma) family kinases, an important class of protein kinases, play key roles in cell signaling and immune regulation. In this review, the association between the pathogenesis of alopecia areata and the structure and regulatory mechanisms of TEC family kinases in normal physiological processes, is explored. Furthermore, the potential clinical applications of TEC kinases and their inhibitors are highlighted by summarizing current insights into their mechanisms of action, clinical applications, and recent advancements in TEC kinase inhibitor research.
摘要：
在肝细胞癌中表达的TEC（酪氨酸激酶）家族激酶，一类重要的蛋白激酶，在细胞信号传导和免疫调节中起关键作用。在这次审查中,斑秃的发病机制与正常生理过程中TEC家族激酶的结构和调节机制之间的关系，正在探索。此外，通过总结目前对其作用机制的见解，突出了TEC激酶及其抑制剂的潜在临床应用，临床应用，以及TEC激酶抑制剂研究的最新进展。
