Abstract：
Cerebrovascular accidents are uncommon but devastating complications of sickle cell disease (SCD). Notably, cerebral sinovenous thrombosis is rarely reported in SCD and poses a therapeutic dilemma regarding anticoagulation. Herein, we describe a challenging case of a patient with sickle thalassaemia admitted to the hospital with recurrent haemorrhagic infarct secondary to cerebral sinus thrombosis. The patient was successfully treated with anticoagulation without neurological deficit. No embolic or other thrombotic aetiology was found, and the stroke was presumed due to sickle cell disease, leading to a hypercoagulable state. Our case report highlights the value of early recognition of this rare but potentially life-threatening condition in SCD, considers other options of anticoagulation therapy and emphasises the importance of close multidisciplinary follow-up particularly post hospital discharge.
摘要：
脑血管意外是镰状细胞病（SCD）的罕见但破坏性的并发症。值得注意的是,在SCD中很少报道脑窦静脉血栓形成,并且在抗凝治疗方面存在两难问题.在这里，我们描述了一例有挑战性的病例,患者因继发于脑窦血栓形成的复发性出血性梗塞入院治疗镰状地中海贫血.患者成功接受抗凝治疗，无神经功能缺损。未发现栓塞或其他血栓性病因，推测中风是由于镰状细胞病，导致高凝状态。我们的病例报告强调了早期识别这种罕见但可能危及生命的SCD疾病的价值，考虑抗凝治疗的其他选择,并强调密切多学科随访的重要性,尤其是出院后.
