关键词: Imported infections Infecciones importadas Kidney transplant Serology Serología Trasplante renal Tropical Tropicales

Mesh : Humans Kidney Transplantation Cross-Sectional Studies Male Female Middle Aged Adult Communicable Diseases, Imported / epidemiology diagnosis Prevalence Transients and Migrants / statistics & numerical data Mass Screening Referral and Consultation / statistics & numerical data Strongyloidiasis / diagnosis epidemiology

来  源:   DOI:10.1016/j.nefroe.2024.07.006

Abstract:
Kidney transplantation (KT) should be postponed in those people with active bacterial, fungal, viral and parasitic processes, since these must be treated and resolved previously. The objective of this study is to present the screening circuit implemented by the Nephrology clinic and describe the prevalence of tropical and imported infections in KT candidates born or coming from endemic areas.
Descriptive cross-sectional study, carried out in 2021. Sociodemographic and clinical variables, serological data of general infections and specific tests of tropical infectious diseases were collected. A descriptive analysis of the data was carried out.
67 TR candidates from Latin America (32.8%), North Africa (22.4%), Sub-Saharan Africa (14.9%) and Asia (29.9%) were included. 68.7% were men and the mean age was 48.9 ± 13.5 years. After the general and specific studies, 42 (62.7%) patients were referred to the Infectious Diseases Service to complete this study or indicate treatment. 35.8% of the patients had eosinophilia, and in one case parasites were detected in feces at the time of the study. Serology for strongyloidiasis was positive in 18 (26.9%) cases, while positive serology for other tropical infections was hardly detected. 34.3% of patients had latent tuberculosis infection.
The prevalence of tropical and imported infections in migrant candidates for RT was low, except for strongyloidiasis and latent tuberculosis infection. Its detection and treatment are essential to avoid serious complications in post-TR. To this end, the implementation of an interdisciplinary screening program from the KT access consultation is feasible, necessary and useful.
摘要:
目的:对于细菌活跃的患者,应推迟肾移植(KT)。真菌,病毒和寄生过程,因为这些必须事先处理和解决。这项研究的目的是介绍肾脏病诊所实施的筛查电路,并描述出生或来自流行地区的KT候选人中热带和输入性感染的患病率。
方法:描述性横断面研究,2021年进行。社会人口统计学和临床变量,收集了一般感染的血清学数据和热带传染病的特定测试。对数据进行了描述性分析。
结果:来自拉丁美洲的67名TR候选人(32.8%),北非(22.4%),包括撒哈拉以南非洲(14.9%)和亚洲(29.9%)。68.7%为男性,平均年龄为48.9±13.5岁。经过一般和具体的研究,42名(62.7%)患者被转介到传染病服务处完成这项研究或表示治疗。35.8%的患者有嗜酸性粒细胞增多,在一个案例中,在研究时在粪便中检测到寄生虫。在18例(26.9%)病例中,线圆线虫病的血清学检查呈阳性,而几乎没有检测到其他热带感染的阳性血清学。34.3%的患者有潜伏性结核感染。
结论:在接受RT治疗的移民候选人中,热带和输入性感染的患病率较低,除了线虫病和潜伏性结核感染。它的检测和治疗对于避免TR后的严重并发症至关重要。为此,从KT访问咨询中实施跨学科筛选计划是可行的,必要的和有用的。
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