PDF(Pubmed)
Abstract：
UNASSIGNED: To compare the efficacy, safety and patients\' quality of life of radiofrequency ablation (RFA) and surgery in the treatment of papillary thyroid microcarcinoma (PTMC).
UNASSIGNED: MEDLINE, EMBASE, Cochrane, CNKI and other databases were searched for studies on radiofrequency ablation versus traditional surgery for PTMC up to October 2022. RevMan5.4 software was used for Meta-analysis.
UNASSIGNED: 10 articles were selected from 392 articles, including 873 cases of radiofrequency ablation and 781 cases of open surgery. After meta-analysis, the incidence of postoperative complications in the radiofrequency ablation group was lower than that in the surgery group, and the difference was statistically significant [OR=0.24, 95%CI (0.14,0.41), P<0.001]. There were no significant differences in lymph node metastasis rate, local recurrence rate, and new tumor rate between the two groups [OR=1.6, 95%CI (0.21, 12.41), P>0.05; OR=0.85, 95%CI (0.05, 13.8), P>0.05; OR=0.12, 95%CI (0.01, 0.98), P>0.05]. The treatment time and hospital stay in the radiofrequency ablation group were shorter than those in the open surgery group [MD=-49.99, 95%CI (-62.02, -37.97), P<0.001; MD=-5.21, 95%CI(-7.19,-3.23),P<0.001], and the cost was significantly lower than that of the traditional surgery group [SMD=-14.97, 95%CI (-19.14, -10.81), P<0.001]. The quality of life of patients in the radiofrequency ablation group was higher than that in the surgery group [MD=-1.61, 95%CI (-2.06, -1.17), P<0.001].
UNASSIGNED: Compared with traditional open surgery, radiofrequency ablation for papillary thyroid microcarcinoma has the advantages of less trauma, fewer complications, faster recovery and higher quality of life. The indications need to be strictly controlled in the treatment.
UNASSIGNED: https://www.crd.york.ac.uk/PROSPERO/, identifier (CRD42022374987).
UNASSIGNED: MEDLINE, EMBASE, Cochrane, CNKI and other databases were searched for studies on radiofrequency ablation versus traditional surgery for PTMC up to October 2022. RevMan5.4 software was used for Meta-analysis.
UNASSIGNED: 10 articles were selected from 392 articles, including 873 cases of radiofrequency ablation and 781 cases of open surgery. After meta-analysis, the incidence of postoperative complications in the radiofrequency ablation group was lower than that in the surgery group, and the difference was statistically significant [OR=0.24, 95%CI (0.14,0.41), P<0.001]. There were no significant differences in lymph node metastasis rate, local recurrence rate, and new tumor rate between the two groups [OR=1.6, 95%CI (0.21, 12.41), P>0.05; OR=0.85, 95%CI (0.05, 13.8), P>0.05; OR=0.12, 95%CI (0.01, 0.98), P>0.05]. The treatment time and hospital stay in the radiofrequency ablation group were shorter than those in the open surgery group [MD=-49.99, 95%CI (-62.02, -37.97), P<0.001; MD=-5.21, 95%CI(-7.19,-3.23),P<0.001], and the cost was significantly lower than that of the traditional surgery group [SMD=-14.97, 95%CI (-19.14, -10.81), P<0.001]. The quality of life of patients in the radiofrequency ablation group was higher than that in the surgery group [MD=-1.61, 95%CI (-2.06, -1.17), P<0.001].
UNASSIGNED: Compared with traditional open surgery, radiofrequency ablation for papillary thyroid microcarcinoma has the advantages of less trauma, fewer complications, faster recovery and higher quality of life. The indications need to be strictly controlled in the treatment.
UNASSIGNED: https://www.crd.york.ac.uk/PROSPERO/, identifier (CRD42022374987).
摘要：
■为了比较疗效，在甲状腺乳头状微小癌（PTMC）的治疗中，射频消融（RFA）和手术的安全性和患者的生活质量。
■MEDLINE,EMBASE,科克伦,截至2022年10月，在CNKI和其他数据库中搜索了PTMC的射频消融与传统手术的研究。采用RevMan5.4软件进行Meta分析。
■从392篇文章中选出10篇文章，其中射频消融873例,开放手术781例。经过荟萃分析，射频消融术组术后并发症发生率低于手术组,差异有统计学意义[OR=0.24,95CI(0.14,0.41),P<0.001]。淋巴结转移率差异无统计学意义,局部复发率,两组间的新瘤率[OR=1.6,95CI(0.21,12.41),P>0.05；OR=0.85，95CI（0.05，13.8），P>0.05；OR=0.12，95CI（0.01，0.98），P>0.05]。射频消融组的治疗时间和住院时间均短于开放手术组[MD=-49.99,95CI(-62.02,-37.97),P<0.001；MD=-5.21，95CI（-7.19，-3.23），P<0.001],且费用明显低于传统手术组[SMD=-14.97,95CI(-19.14,-10.81),P<0.001]。射频消融组患者的生活质量高于手术组[MD=-1.61,95CI(-2.06,-1.17),P<0.001]。
■与传统的开放手术相比，甲状腺乳头状微小癌的射频消融具有创伤小的优点,并发症少,更快的恢复和更高的生活质量。在治疗中需要严格控制适应症。
■https://www.crd.约克。AC.英国/PROSPERO/,标识符(CRD42022374987)。
■MEDLINE,EMBASE,科克伦,截至2022年10月，在CNKI和其他数据库中搜索了PTMC的射频消融与传统手术的研究。采用RevMan5.4软件进行Meta分析。
■从392篇文章中选出10篇文章，其中射频消融873例,开放手术781例。经过荟萃分析，射频消融术组术后并发症发生率低于手术组,差异有统计学意义[OR=0.24,95CI(0.14,0.41),P<0.001]。淋巴结转移率差异无统计学意义,局部复发率,两组间的新瘤率[OR=1.6,95CI(0.21,12.41),P>0.05；OR=0.85，95CI（0.05，13.8），P>0.05；OR=0.12，95CI（0.01，0.98），P>0.05]。射频消融组的治疗时间和住院时间均短于开放手术组[MD=-49.99,95CI(-62.02,-37.97),P<0.001；MD=-5.21，95CI（-7.19，-3.23），P<0.001],且费用明显低于传统手术组[SMD=-14.97,95CI(-19.14,-10.81),P<0.001]。射频消融组患者的生活质量高于手术组[MD=-1.61,95CI(-2.06,-1.17),P<0.001]。
■与传统的开放手术相比，甲状腺乳头状微小癌的射频消融具有创伤小的优点,并发症少,更快的恢复和更高的生活质量。在治疗中需要严格控制适应症。
■https://www.crd.约克。AC.英国/PROSPERO/,标识符(CRD42022374987)。
