PDF(Pubmed)
Abstract：
BACKGROUND: The etiological diagnosis of intracranial hypertension is quite complicated but important in clinical practice. Some common causes are craniocerebral injury, intracranial space-occupying lesion, subarachnoid hemorrhage, and hydrocephalus. When a patient presents with intracranial hypertension, the common causes are to be considered first so that other causes would be dismissed. With the morbidity lower than 9%, neuromelanin is very rare. Common symptoms include nerve damage symptoms, epilepsy, psychiatric symptoms, and cognitive disorders.
METHODS: We present a patient with melanoma which manifested with isolated intracranial hypertension without any other neurological signs. A 22-year-old male had repeated nausea and vomiting for 2 mo with Babinski sign (+) on both sides, nuchal rigidity, and subarachnoid hemorrhage. He had been diagnosed with melanoma and was given surgery and whole-brain radiation. Ultimately, the patient died 2 mo later.
CONCLUSIONS: Malignant melanoma should be taken into consideration in the differential diagnosis of intracranial hypertension.
METHODS: We present a patient with melanoma which manifested with isolated intracranial hypertension without any other neurological signs. A 22-year-old male had repeated nausea and vomiting for 2 mo with Babinski sign (+) on both sides, nuchal rigidity, and subarachnoid hemorrhage. He had been diagnosed with melanoma and was given surgery and whole-brain radiation. Ultimately, the patient died 2 mo later.
CONCLUSIONS: Malignant melanoma should be taken into consideration in the differential diagnosis of intracranial hypertension.
摘要：
背景：颅内高压的病因诊断相当复杂，但在临床实践中很重要。一些常见的原因是颅脑损伤，颅内占位性病变,蛛网膜下腔出血,和脑积水.当病人出现颅内高压时，首先要考虑常见的原因，以便排除其他原因。发病率低于9%，神经黑色素非常罕见。常见症状包括神经损伤症状，癫痫,精神症状,和认知障碍。
方法：我们介绍了一名黑色素瘤患者，表现为孤立的颅内高压，没有任何其他神经系统症状。一名22岁的男性反复恶心和呕吐2个月，两侧都有Babinski标志（），颈部刚性，和蛛网膜下腔出血.他被诊断出患有黑色素瘤，并接受了手术和全脑放疗。最终,病人2个月后死亡。
结论：颅内高压的鉴别诊断应考虑恶性黑色素瘤。
方法：我们介绍了一名黑色素瘤患者，表现为孤立的颅内高压，没有任何其他神经系统症状。一名22岁的男性反复恶心和呕吐2个月，两侧都有Babinski标志（），颈部刚性，和蛛网膜下腔出血.他被诊断出患有黑色素瘤，并接受了手术和全脑放疗。最终,病人2个月后死亡。
结论：颅内高压的鉴别诊断应考虑恶性黑色素瘤。
