%0 Case Reports
%T Intracranial hypertension as the primary symptom of malignant melanoma: A case report.
%A Xie HT
%A An DH
%A Wu DB
%J World J Clin Cases
%V 12
%N 21
%D 2024 Jul 26
%M 39070805
%F 1.534
%R 10.12998/wjcc.v12.i21.4836
%X <B>BACKGROUND: </B>The etiological diagnosis of intracranial hypertension is quite complicated but important in clinical practice. Some common causes are craniocerebral injury, intracranial space-occupying lesion, subarachnoid hemorrhage, and hydrocephalus. When a patient presents with intracranial hypertension, the common causes are to be considered first so that other causes would be dismissed. With the morbidity lower than 9%, neuromelanin is very rare. Common symptoms include nerve damage symptoms, epilepsy, psychiatric symptoms, and cognitive disorders.<BR><B>METHODS: </B>We present a patient with melanoma which manifested with isolated intracranial hypertension without any other neurological signs. A 22-year-old male had repeated nausea and vomiting for 2 mo with Babinski sign (+) on both sides, nuchal rigidity, and subarachnoid hemorrhage. He had been diagnosed with melanoma and was given surgery and whole-brain radiation. Ultimately, the patient died 2 mo later.<BR><B>CONCLUSIONS: </B>Malignant melanoma should be taken into consideration in the differential diagnosis of intracranial hypertension.