RESULTS: The analysis revealed statistically significant differences in the distributions of genotypes and alleles of the rs4588 polymorphism among the three groups (p < 0.0001). The AC genotype and A allele showed an association with an elevated risk of PCOS and infertility. In this study, no association was found between genotypes and alleles of the rs4588 polymorphism and the risk of RPL in women with PCOS. Subjects with the AA or AC genotype exhibited significantly higher levels of LDL compared to those with the CC genotype.
结果:分析显示,rs4588多态性的基因型和等位基因分布在三组之间具有统计学上的显着差异(p<0.0001)。AC基因型和A等位基因与PCOS和不孕症的风险升高有关。在这项研究中,在PCOS女性患者中,rs4588多态性的基因型和等位基因与RPL风险之间未发现关联.与具有CC基因型的受试者相比,具有AA或AC基因型的受试者表现出显著更高水平的LDL。