PDF(Pubmed)
Abstract：
The clinical spectrum of invasive pulmonary aspergillosis (IPA) has expanded in recent decades. A large group of patients admitted to intensive care units (ICU) is indeed susceptible to the development of IPA. Although timely diagnosis and antifungal therapy of IPA in this expanding population is crucial to prevent IPA-related deaths, the magnitude of the favorable prognostic impact of antifungal therapy is difficult to measure precisely. In our opinion, the development of standardized research definitions could have favorable implications for further improving our ability both to measure the favorable effect of antifungal treatment and to prevent IPA-related death in ICU patients.
摘要：
近几十年来，侵袭性肺曲霉病（IPA）的临床范围不断扩大。进入重症监护病房（ICU）的一大群患者确实容易发生IPA。尽管在这个不断扩大的人群中及时诊断和抗真菌治疗IPA对于预防IPA相关死亡至关重要，抗真菌治疗对预后的有利影响的大小难以精确测量.在我们看来,标准化研究定义的发展可能对进一步提高我们在ICU患者中评估抗真菌治疗的有利效果和预防IPA相关死亡的能力具有有利意义.
