PDF(Pubmed)
Abstract：
A series of fluorescent molecules with 1,1-dimethylnaphthalene-2(1H)-one as the core were synthesized to overcome aggregation quenching and emit bright green fluorescence. The low molecular weight of these molecules led to them to smoothly pass through the cell membrane and penetrate deep into the nucleus to emit the corresponding fluorescence. Among them, NC-4-Br and NC-5-3O have good optical and in vitro properties and showed potential for use as fluorescent probes.
摘要：
合成了一系列以1,1-二甲基萘-2(1H)-酮为核心的荧光分子，以克服聚集猝灭并发出明亮的绿色荧光。这些分子的低分子量导致它们平稳地穿过细胞膜并深入细胞核以发射相应的荧光。其中,NC-4-Br和NC-5-3O具有良好的光学和体外特性，并显示出用作荧光探针的潜力。
