METHODS: The data for this study were obtained from Taiwan\'s Longitudinal Health Insurance Database 2010. The sample consisted of 150,916 patients who were newly diagnosed with peripheral vestibular disorders as cases and 452,748 propensity-score-matching controls without peripheral vestibular disorders. We utilized multivariate logistic regression models to quantitatively evaluate the association between peripheral vestibular disorders and diabetes while considering factors such as sex, age, geographic location, monthly income, urbanization level of the patient\'s residence, coronary heart disease, hypertension, and hyperlipidemia.
RESULTS: The chi-squared test indicates that diabetes was more common in the peripheral vestibular disorder group compared to controls (20.6% vs. 15.1%, p < 0.001). Of all sampled patients, the adjusted odds ratio for diabetes was 1.597 (95% CI = 1.570~1.623) for those with peripheral vestibular disorders when compared to controls, while patients with Ménière\'s disease, benign paroxysmal positional vertigo, unilateral vestibulopathy, and other peripheral vestibular disorders had respective adjusted odds ratios of diabetes at 1.566 (95% CI = 1.498~1.638), 1.677 (95% CI = 1.603~1.755), 1.592 (95% CI = 1.504~1.685), and 1.588 (95% CI = l.555~1.621) in comparison to controls.
CONCLUSIONS: Our research has revealed an association between diabetes and an increased susceptibility to peripheral vestibular disorders.
方法:本研究的数据来自台湾的2010年纵向健康保险数据库。样本包括150,916例新诊断为周围前庭疾病的患者和452,748例没有周围前庭疾病的倾向评分匹配对照。我们利用多变量逻辑回归模型来定量评估外周前庭疾病和糖尿病之间的关联,同时考虑性别等因素。年龄,地理位置,月收入,患者居住地的城市化水平,冠心病,高血压,和高脂血症。
结果:卡方测试表明,与对照组相比,糖尿病在周围前庭障碍组中更常见(20.6%vs.15.1%,p<0.001)。在所有样本患者中,与对照组相比,患有外周前庭疾病的糖尿病的校正比值比为1.597(95%CI=1.570〜1.623),而患有梅尼埃病的患者,良性阵发性位置性眩晕,单侧前庭病,和其他周围性前庭疾病的糖尿病的调整比值比分别为1.566(95%CI=1.498〜1.638),1.677(95%CI=1.603~1.755),1.592(95%CI=1.504~1.685),与对照组相比,为1.588(95%CI=1.555~1.621)。
结论:我们的研究揭示了糖尿病与外周前庭疾病易感性增加之间的关联。