%0 Journal Article
%T Association of Peripheral Vestibular Disorder with Diabetes: A Population-Based Study.
%A Yang TH
%A Chen CH
%A Cheng YF
%A Lin HC
%A Chen CS
%J J Pers Med
%V 14
%N 7
%D 2024 Jul 19
%M 39064022
%F 3.508
%R 10.3390/jpm14070768
%X <B>BACKGROUND: </B>This study aimed to investigate the association of peripheral vestibular disorders with type 1 and type 2 diabetes using a population-based dataset.<BR><B>METHODS: </B>The data for this study were obtained from Taiwan's Longitudinal Health Insurance Database 2010. The sample consisted of 150,916 patients who were newly diagnosed with peripheral vestibular disorders as cases and 452,748 propensity-score-matching controls without peripheral vestibular disorders. We utilized multivariate logistic regression models to quantitatively evaluate the association between peripheral vestibular disorders and diabetes while considering factors such as sex, age, geographic location, monthly income, urbanization level of the patient's residence, coronary heart disease, hypertension, and hyperlipidemia.<BR><B>RESULTS: </B>The chi-squared test indicates that diabetes was more common in the peripheral vestibular disorder group compared to controls (20.6% vs. 15.1%, p < 0.001). Of all sampled patients, the adjusted odds ratio for diabetes was 1.597 (95% CI = 1.570~1.623) for those with peripheral vestibular disorders when compared to controls, while patients with Ménière's disease, benign paroxysmal positional vertigo, unilateral vestibulopathy, and other peripheral vestibular disorders had respective adjusted odds ratios of diabetes at 1.566 (95% CI = 1.498~1.638), 1.677 (95% CI = 1.603~1.755), 1.592 (95% CI = 1.504~1.685), and 1.588 (95% CI = l.555~1.621) in comparison to controls.<BR><B>CONCLUSIONS: </B>Our research has revealed an association between diabetes and an increased susceptibility to peripheral vestibular disorders.