PDF(Pubmed)
Abstract：
This year marks the 35th anniversary of Professor Walter Wahli\'s discovery of the PPARs (Peroxisome Proliferator-Activated Receptors) family of nuclear hormone receptors. To mark the occasion, the editors of the scientific periodical Biomolecules decided to publish a special issue in his honor. This paper summarizes what is known about PPARs and shows how trends have changed and how research on PPARs has evolved. The article also highlights the importance of PPARs and what role they play in various diseases and ailments. The paper is in a mixed form; essentially it is a review article, but it has been enriched with the results of our experiments. The selection of works was subjective, as there are more than 200,000 publications in the PubMed database alone. First, all papers done on an animal model were discarded at the outset. What remained was still far too large to describe directly. Therefore, only papers that were outstanding, groundbreaking, or simply interesting were described and briefly commented on.
摘要：
今年是WalterWahli教授发现PPAR（过氧化物酶体增殖物激活受体）核激素受体家族35周年。为了纪念这个场合，科学期刊《生物分子》的编辑决定以他的荣誉出版一期特刊。本文总结了有关PPAR的知识，并展示了趋势如何变化以及PPAR的研究如何发展。文章还强调了PPAR的重要性以及它们在各种疾病和疾病中的作用。这篇论文是混合形式的；本质上是一篇评论文章，但是我们的实验结果丰富了。作品的选择是主观的，因为仅PubMed数据库中就有超过200,000种出版物。首先,一开始就丢弃了所有在动物模型上完成的论文.剩下的仍然太大了，无法直接描述。因此,只有优秀的论文，开创性的,或简单有趣的描述和简要评论。
