Abstract：
Infantile colic (IC) is c is a self-limiting functional gastrointestinal disorder (FGID) with a favorable natural history. Worldwide, IC has a significant impact on many newborns and their families. Although not an indication of an illness, its symptoms are wide and generic and may indicate a potentially serious underlying issue in a tiny percentage of newborns who may require a medical evaluation. The pathogenesis appears to be multifactorial implying a complex relationship between the infant and the environment. One of the most studied theories attributes a key role to the gut microbiota in the pathogenesis of IC. A variety of approaches have been suggested for the clinical management of IC, and several randomized controlled trials have been reported in the literature. Probiotics can change the host\'s microbiota and positively impact health. They may be able to restore balance and create a better intestinal microbiota landscape since there is mounting evidence that the gut microbial environment of colicky newborns differs from that of healthy infants. In this review, we revise the most commonly studied probiotics and mixtures to treat and prevent IC and the most recent recommendations.
摘要：
婴儿绞痛（IC）是一种自限性功能性胃肠道疾病（FGID），具有良好的自然史。全球,IC对许多新生儿及其家庭有重大影响。虽然不是疾病的迹象，它的症状是广泛和普遍的，可能表明一个潜在的严重的潜在问题，在一小部分新生儿谁可能需要医疗评估。发病机理似乎是多因素的，暗示了婴儿与环境之间的复杂关系。研究最多的理论之一将肠道微生物群在IC发病机理中的关键作用归因于。已经提出了多种方法用于IC的临床管理，文献中已经报道了一些随机对照试验。益生菌可以改变宿主的微生物群，并对健康产生积极影响。它们可能能够恢复平衡并创造更好的肠道微生物群景观，因为越来越多的证据表明，绞痛新生儿的肠道微生物环境不同于健康婴儿。在这次审查中,我们修订了治疗和预防IC的最常用益生菌和混合物以及最新建议.
