Abstract：
The novel personal protection equipment based on a face mask equipped with a nanofiber filter functionalized with povidone iodine has been developed and tested in a clinical trial. This nanofiber filter was characterized with a low flow resistance and, thus, allowed comfortable breathing. The performed study proved that the novel nanofiber filter with incorporated povidone-iodine was characterized with a slow release of iodine which minimized side effects but kept disinfection efficiency. Our clinical study performed on 207 positively tested SARS-CoV-2 patients wearing the PPE for 4-8 hours daily for 1 to 4 days has shown that even the iodine amount as low as 0.00028 ppm was sufficient to significantly decrease the reproduction number and, very importantly, to protect against severe course of disease.
摘要：
已经开发并在临床试验中测试了基于配备有聚维酮碘功能化的纳米纤维过滤器的面罩的新型个人防护设备。这种纳米纤维过滤器的特点是具有低的流动阻力，因此，允许舒适的呼吸。进行的研究证明，掺入聚维酮碘的新型纳米纤维过滤器的特征是碘的缓慢释放，使副作用最小化，但保持了消毒效率。我们的临床研究对207名接受过阳性测试的SARS-CoV-2患者每天佩戴PPE4-8小时，持续1至4天，表明即使碘量低至0.00028ppm也足以显着减少繁殖次数，非常重要的是,以防止严重的病程。
