人类小胶质细胞作为神经发育疾病模型中的治疗靶标。
关键词: ADH-503 CD11b MECP2 chromatin iPSC integrin microglia neurodevelopment neurons phagocytosis stem cells synaptogenesis
Mesh : Microglia / metabolism Humans Methyl-CpG-Binding Protein 2 / genetics metabolism Animals Phagocytosis Mice Neurodevelopmental Disorders / genetics metabolism pathology Coculture Techniques Disease Models, Animal Mice, Knockout Synapses / metabolism Neurons / metabolism
来 源:
DOI:10.1016/j.stemcr.2024.06.013
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