METHODS: A 57-year-old female with a mass on the left side of the floor of the mouth that had been present for 2 months. The computed tomography scan of the neck revealed a nodular abnormal density shadow in the left sublingual area, measuring approximately 2.6 cm × 1.9 cm.
METHODS: Primary HCCC of the sublingual gland.
METHODS: The patient underwent surgical treatment and reconstruction using a left anterolateral femoral free flap, which showed immunohistochemical positivity for CK 5/6, CK 7, CK (AE1/AE3), and Ki-67 (<5%), but negative for SMA and S-100.
RESULTS: No recurrence was observed during the 12-month postoperative follow-up period.
CONCLUSIONS: The absence of characteristic clinical manifestations makes HCCC highly susceptible to misdiagnoses. This case presents a rare instance of HCCC in the sublingual gland, providing a reference for the clinical diagnosis and treatment of the disease.
方法:一名57岁女性,嘴底左侧有肿块,已经存在2个月。颈部计算机断层扫描显示左侧舌下区域有结节状异常密度影,约2.6厘米×1.9厘米。
方法:舌下腺原发性HCCC。
方法:患者使用左股前外侧游离皮瓣进行手术治疗和重建,显示CK5/6,CK7,CK(AE1/AE3)的免疫组织化学阳性,和Ki-67(<5%),但SMA和S-100阴性.
结果:术后12个月随访期间未见复发。
结论:由于缺乏特征性临床表现,HCCC极易被误诊。此例表现为舌下腺HCCC的罕见病例,为该病的临床诊断和治疗提供参考。