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Abstract：
A total of 769 wheat kernels collected from six provinces in China were analyzed for beauvericin (BEA) and four enniatins (ENNs), namely, ENA, ENA1, ENB and ENB1, using a solid phase extraction (SPE) technique with ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The results show that the predominant toxin was BEA, which had a maximum of 387.67 μg/kg and an average of 37.69 μg/kg. With regard to ENNs, the prevalence and average concentrations of ENB and ENB1 were higher than those of ENA and ENA1. The geographical distribution of BEA and ENNs varied. Hubei and Shandong exhibited the highest and lowest positive rates of BEA and ENNs (13.46% and 87.5%, respectively). However, no significant difference was observed among these six provinces. There was a co-occurrence of BEA and ENNs, and 42.26% of samples were simultaneously detected with two or more toxins. Moreover, a significant linear correlation in concentrations was observed between the four ENN analogs (r range: 0.75~0.96, p < 0.05). This survey reveals that the contamination and co-contamination of BEA and ENNs in Chinese wheat kernels were very common.
摘要：
从中国六个省收集的769个小麦籽粒进行了白僵素(BEA)和4种脑内素(ENN)的分析,即,ENA,ENA1，ENB和ENB1，采用固相萃取（SPE）技术与超高效液相色谱-串联质谱（UPLC-MS/MS）。结果表明，主要的毒素是BEA，最大值为387.67μg/kg，平均值为37.69μg/kg。关于ENN，ENB和ENB1的患病率和平均浓度高于ENA和ENA1.BEA和ENN的地理分布各不相同。湖北和山东的BEA和ENNs阳性率最高和最低（分别为13.46％和87.5％，分别)。然而,这六个省之间没有显着差异。BEA和ENN同时发生，42.26%的样本同时检测到两种或两种以上毒素。此外，在四种ENN类似物之间观察到浓度的显著线性相关性(r范围:0.75~0.96,p<0.05)。这项调查表明，中国小麦籽粒中BEA和ENN的污染和共污染非常普遍。
