关键词: local control pancreatic insulinoma stereotactic body radiation therapy

Mesh : Humans Insulinoma / radiotherapy Radiosurgery / methods Pancreatic Neoplasms / radiotherapy Female Middle Aged Male Adult

来  源:   DOI:10.3390/curroncol31070307   PDF(Pubmed)

Abstract:
Insulinoma is the most common functional neuroendocrine tumor of the pancreas, with the main clinical symptom being hypoglycemia. The standard treatment is surgery, but some patients are not eligible for surgery, while in those operated on, the risk of perioperative complications is up to 30%. Diazoxide treatment to prevent hypoglycemia is effective only in 50% of patients. To prevent tumor growth and hormonal excess, stereotactic radiotherapy may be an alternative to surgical treatment. In our paper, we present two cases of patients with insulinoma treated successfully with stereotactic body radiation therapy (SBRT).
摘要:
胰岛素瘤是胰腺最常见的功能性神经内分泌肿瘤,主要临床症状为低血糖。标准的治疗方法是手术,但是有些病人没有资格接受手术,而在那些手术中,围手术期并发症的风险高达30%。二氮嗪治疗预防低血糖仅对50%的患者有效。为了防止肿瘤生长和荷尔蒙过量,立体定向放疗可能是手术治疗的替代方案.在我们的论文中,我们介绍了2例接受立体定向放射治疗(SBRT)成功治疗的胰岛素瘤患者.
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