关键词: Cancer hyposalivation oral cancer prevalence xerostomia

来  源:   DOI:10.4103/jispcd.jispcd_156_23   PDF(Pubmed)

Abstract:
UNASSIGNED: It has been speculated that the prevalence of xerostomia and hyposalivation might be higher among individuals attending oral cancer screening than among members of the general population. Therefore, this study investigated the prevalence of these conditions and their associated factors among individuals taking part in oral cancer screening and residing in the northeastern provinces of Thailand.
UNASSIGNED: This cross-sectional study recruited convenient individuals aged ≥40 years with at least one oral cancer risk factor. In total, 561 participants were included. Demographic characteristics and relevant oral cancer risk factors were recorded. A questionnaire comprising five items was used to assess xerostomia. Participants were then categorized into two groups based on the absence or presence of xerostomia. Subsequently, the stimulated salivary flow rate was assessed using the spitting technique to identify hyposalivation. Participants were then separated into two groups depending on the absence or presence of hyposalivation. Univariate and multivariate logistic regression analyses were then performed to identify factors associated with xerostomia or hyposalivation.
UNASSIGNED: The mean age of participants was 65.62 ± 9.70 years, and approximately 60% of participants were post-menopausal women. The prevalence of xerostomia was 43.85%, and the prevalence of hyposalivation was 61.50%. It was revealed that age ≥65 years (odds ratio [OR] = 1.57, P = 0.02) and burning sensation in the mouth (OR = 5.36, P < 0.001) were strongly associated with xerostomia. Female participants were more likely to exhibit hyposalivation (OR = 2.38, P = 0.001). Oral cancer risk factors were not associated with xerostomia or hyposalivation.
UNASSIGNED: In this study, age ≥65 years and burning sensation were identified as risk factors for xerostomia, whereas female sex was a risk factor for hyposalivation. Dentists should be aware of both conditions. Various interventions to alleviate dry mouth symptoms might be useful for individuals with these risk factors.
摘要:
据推测,参加口腔癌筛查的个体口干症和唾液分泌减少的患病率可能高于普通人群。因此,本研究调查了参与口腔癌筛查并居住在泰国东北部省份的个体中这些疾病的患病率及其相关因素.
这项横断面研究招募了年龄≥40岁且至少有一种口腔癌危险因素的方便个体。总的来说,包括561名参与者。记录人口统计学特征和相关口腔癌危险因素。使用包含五个项目的问卷来评估口干症。然后根据是否存在口干症将参与者分为两组。随后,使用吐痰技术评估刺激的唾液流速,以确定唾液分泌减少.然后根据是否存在唾液分泌不足将参与者分为两组。然后进行单变量和多变量逻辑回归分析,以确定与口干症或唾液分泌减少相关的因素。
参与者的平均年龄为65.62±9.70岁,约60%的参与者是绝经后妇女.口干症患病率为43.85%,唾液分泌减少的患病率为61.50%。发现年龄≥65岁(比值比[OR]=1.57,P=0.02)和口腔灼热感(OR=5.36,P<0.001)与口干症密切相关。女性参与者更容易出现唾液分泌不足(OR=2.38,P=0.001)。口腔癌危险因素与口干症或唾液分泌不足无关。
在这项研究中,年龄≥65岁和烧灼感被确定为口干症的危险因素,而女性是唾液分泌不足的危险因素。牙医应该了解这两种情况。缓解口干症状的各种干预措施可能对具有这些危险因素的个体有用。
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