Abstract：
The Streptomyces chassis serves as an important platform for efficient biomanufacture of diverse secondary metabolite (SM) compounds, but the current chassis lacks compatibility for integration of these SM biosynthetic pathways reliably and consistently. This forum discusses harnessing naturally evolved multifaceted switches to reprogram the Streptomyces chassis for biomanufacturing applications.
摘要：
链霉菌底盘是高效生物制造多种次生代谢产物（SM）化合物的重要平台，但目前的底盘缺乏这些SM生物合成途径可靠和一致地整合的兼容性。该论坛讨论了利用自然进化的多方面开关来重新编程链霉菌底盘以用于生物制造应用。
