%0 Journal Article
%T Reprogramming naturally evolved switches for Streptomyces chassis development.
%A Yan H
%A Li S
%A Wang W
%J Trends Biotechnol
%V 0
%N 0
%D 2024 Jul 24
%M 39054219
%F 21.942
%R 10.1016/j.tibtech.2024.07.001
%X The Streptomyces chassis serves as an important platform for efficient biomanufacture of diverse secondary metabolite (SM) compounds, but the current chassis lacks compatibility for integration of these SM biosynthetic pathways reliably and consistently. This forum discusses harnessing naturally evolved multifaceted switches to reprogram the Streptomyces chassis for biomanufacturing applications.