关键词: Asymmetric hearing loss Brain plasticity Cochlear implantation Unilateral deafness

Mesh : Humans Cochlear Implantation / instrumentation Male Cochlear Implants Positron-Emission Tomography Female Middle Aged Adult Neuronal Plasticity Acoustic Stimulation Adaptation, Physiological Brain Mapping / methods Persons With Hearing Impairments / psychology rehabilitation Brain / diagnostic imaging physiopathology Hearing Case-Control Studies Auditory Perception Hearing Loss, Unilateral / physiopathology rehabilitation diagnostic imaging psychology Deafness / physiopathology diagnostic imaging rehabilitation surgery Aged Correction of Hearing Impairment Discrimination, Psychological

来  源:   DOI:10.1016/j.heares.2024.109079

Abstract:
Brain plasticity refers to the brain\'s ability to reorganize its structure or function in response to experiences, learning, and environmental influences. This phenomenon is particularly significant in individuals with deafness, as the brain adapts to compensate for the lack of auditory stimulation. The aim of this study is to investigate whether cochlear implantation can restore a normal pattern of brain activation following auditory stimulation in cases of asymmetric hearing loss. We used a PET-scan technique to assess brain activity after cochlear implantation, specifically during an auditory voice/non-voice discrimination task. The results indicated a nearly normal pattern of brain activity during the auditory discrimination task, except for increased activation in areas related to attentional processes compared to controls. Additionally, brain activity at rest showed significant changes in implanted participants, including cross modal visuo-auditory processing. Therefore, cochlear implants can restore the brain\'s activation pattern through long-term adaptive adjustments in intrinsic brain activity.
摘要:
大脑可塑性是指大脑根据经验重组其结构或功能的能力,学习,和环境影响。这种现象在患有耳聋的个体中尤其显著,因为大脑会适应补偿听觉刺激的缺乏。这项研究的目的是研究在不对称听力损失的情况下,人工耳蜗植入是否可以在听觉刺激后恢复正常的大脑激活模式。我们使用PET扫描技术来评估人工耳蜗植入后的大脑活动,特别是在听觉语音/非语音辨别任务期间。结果表明,在听觉辨别任务期间,大脑活动的模式几乎正常,与对照组相比,与注意过程相关的区域激活增加。此外,休息时的大脑活动显示植入参与者的显着变化,包括跨模态视觉-听觉处理。因此,耳蜗植入物可以通过长期的内在大脑活动的适应性调整来恢复大脑的激活模式。
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