Abstract：
Infection is a major cause of treatment-related morbidity and mortality in pediatric acute lymphoblastic leukemia (ALL). Most children with ALL who develop life-threatening bacterial infections do so during induction therapy. We describe a rare case of ALL presenting simultaneously with Streptococcus agalactiae group B Streptococcus bacteremia and meningitis in a 3-year-old girl. She received appropriate antimicrobial therapy and a 2-drug early induction regimen consisting of vincristine and dexamethasone, leading to slow neurologic recovery and a favorable initial response to anti-neoplastic therapy as evidenced by minimal residual disease of 1.12% on day 15 of induction.
摘要：
感染是小儿急性淋巴细胞白血病（ALL）治疗相关发病率和死亡率的主要原因。大多数患有ALL的儿童在诱导治疗期间发生威胁生命的细菌感染。我们描述了一个3岁女孩中ALL与无乳链球菌B组链球菌菌血症和脑膜炎同时出现的罕见病例。她接受了适当的抗菌治疗和2种药物的早期诱导方案，包括长春新碱和地塞米松，导致神经系统恢复缓慢和对抗肿瘤治疗的良好初始反应，诱导第15天的微小残留病为1.12％。
