%0 Case Reports
%T Simultaneous Presentation of B-Acute Lymphoblastic Leukemia and Streptococcus agalactiae Meningitis in a 3-Year-old Girl.
%A Purvis K
%A Hiskey L
%A Khanlari M
%A Mead PE
%A Holland AC
%A Bag AK
%A Adderson E
%A Inaba H
%J J Pediatr Hematol Oncol
%V 46
%N 6
%D 2024 Aug 1
%M 39051638
%F 1.17
%R 10.1097/MPH.0000000000002921
%X Infection is a major cause of treatment-related morbidity and mortality in pediatric acute lymphoblastic leukemia (ALL). Most children with ALL who develop life-threatening bacterial infections do so during induction therapy. We describe a rare case of ALL presenting simultaneously with Streptococcus agalactiae group B Streptococcus bacteremia and meningitis in a 3-year-old girl. She received appropriate antimicrobial therapy and a 2-drug early induction regimen consisting of vincristine and dexamethasone, leading to slow neurologic recovery and a favorable initial response to anti-neoplastic therapy as evidenced by minimal residual disease of 1.12% on day 15 of induction.